6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE
- Product Name
- 6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE
- CAS No.
- 259810-12-3
- Chemical Name
- 6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE
- Synonyms
- 4H,6H,7H-pyrano[4,3-d][1,3]thiazol-2-aMine;6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-AMINE;6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE;4H-Pyrano[4,3-d]thiazol-2-amine, 6,7-dihydro-;6,7-dihydro-4H-pyrano[4,3-d][1,3]thiazol-2-amine;6,7-Dihydro-4H-pyrano[4,3-d]-1,3-thiazol-2-ylamine
- CBNumber
- CB9808566
- Molecular Formula
- C6H8N2OS
- Formula Weight
- 156.21
- MOL File
- 259810-12-3.mol
6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE Property
- Boiling point:
- 353.7±32.0 °C(Predicted)
- Density
- 1.391±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light
- pka
- 4.73±0.20(Predicted)
- Appearance
- Light yellow to yellow Solid
Safety
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D679898
- Product name
- 6,7-Dihydro-4H-pyrano[4,3-D]thiazol-2-ylamine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FD142434
- Product name
- 6,7-Dihydro-4H-pyrano[4,3-d]thiazol-2-amine
- Packaging
- 500mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- 8H70-1-47
- Product name
- 6,7-Dihydro-4H-pyrano[4,3-d]thiazol-2-amine
- Packaging
- 1g
- Price
- $77
- Updated
- 2021/12/16
- Product number
- FD142434
- Product name
- 6,7-Dihydro-4H-pyrano[4,3-d]thiazol-2-amine
- Packaging
- 1g
- Price
- $118
- Updated
- 2021/12/16
- Product number
- W4936
- Product name
- 6,7-Dihydro-4H-pyrano[4,3-d]thiazol-2-amine
- Packaging
- 1g
- Price
- $136
- Updated
- 2021/12/16
6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE Chemical Properties,Usage,Production
Synthesis
29943-42-8
420-04-2
259810-12-3
GENERAL STEPS: Tetrahydro-4H-pyran-4-one (500 mg, 4.99 mmol), sulfur powder (160 mg, 4.99 mmol), cyanamide (210 mg, 4.99 mmol), and pyrrolidine (4 μL, 0.05 mmol) were dissolved in isopropanol (3 mL) and the reaction was stirred for 1.5 hours at room temperature. Upon completion of the reaction, the mixture was partitioned between water and ethyl acetate (EtOAc) and the aqueous phase was extracted with additional ethyl acetate. The organic phases were combined, washed sequentially with water and saturated brine and dried over anhydrous magnesium sulfate (MgSO?). The crude product was purified by fast column chromatography eluting with a gradient of mixed solvents (0-10% MeOH) of dichloromethane (DCM) and methanol (MeOH) to afford 6,7-dihydro-4H-pyrano[4,3-D]thiazol-2-amine as a yellow oil, which was crystallized after standing (500 mg, 64% yield). Mass spectrum (MS): m/z = 156.9 ([M + H]+).
References
[1] Patent: WO2016/1341, 2016, A1. Location in patent: Page/Page column 85
[2] Patent: WO2009/67613, 2009, A1. Location in patent: Page/Page column 129
6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE Suppliers
- Tel
- 025-86918202 4000255188
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- 86-025-86918232
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- China
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- 5000
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- 55
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- +86 (0) 571 85 58 67 18
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- 0086-571-85864795
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- China
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- 18207
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- 021-50795510 4000665055
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- 021-50795055
- sales@accelachem.com
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- China
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- 64
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- +86 (21) 6435-5022
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- China
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- 4267
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- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
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- 12984
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- 021-54849683 13601642561
- Fax
- +86-21-54375689
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- China
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- 86(512)5235 8471 17715136450
- Fax
- 86(512)5235 6881
- sales@shiyabiopharm.com
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- China
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- 4169
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- Tel
- 0512-63970158-603 18018108880
- Fax
- 0512-63971078
- info@lakestarpharma.com
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- China
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- 421
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- +1(858) 699-3322
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- +1(858) 876-1948
- marketing@accelachem.com
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- United States
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- 6024
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- 021-64340559 13651849907;
- Fax
- 021- 64345308
- xinyu_shi@jwypharmlab.com.cn
- Country
- China
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- 12000
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View Lastest Price from 6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE manufacturers
- Product
- 6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE 259810-12-3
- Price
- US $0.01/KG
- Min. Order
- 1KG
- Purity
- 98%; 99%
- Supply Ability
- 500g； 1kg; 25kg
- Release date
- 2020-01-10
- Product
- 6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE 259810-12-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-25