2-(1H-IMIDAZOL-2-YL)-PYRAZINE

Product Name: 2-(1H-IMIDAZOL-2-YL)-PYRAZINE
CAS No.: 119165-68-3
Chemical Name: 2-(1H-IMIDAZOL-2-YL)-PYRAZINE
Synonyms: 2-(1H-2-IMidazolyl)pyrazine;2-(1H-IMIDAZOL-2-YL)-PYRAZINE;Pyrazine, 2-(1H-imidazol-2-yl)-
CBNumber: CB9832785
Molecular Formula: C7H6N4
Formula Weight: 146.15
MOL File: 119165-68-3.mol

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2-(1H-IMIDAZOL-2-YL)-PYRAZINE Property

storage temp.: Sealed in dry,Room Temperature

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AstaTech

Product number: 62612
Product name: 2-(1H-2-IMIDAZOLYL)PYRAZINE
Purity: 97%
Packaging: 0.25G
Price: $24
Updated: 2026/04/30

AstaTech

Product number: 62612
Product name: 2-(1H-2-IMIDAZOLYL)PYRAZINE
Purity: 97%
Packaging: 1G
Price: $97
Updated: 2026/04/30

Matrix Scientific

Product number: 131905
Product name: 2-(1H-Imidazol-2-yl)pyrazine
Packaging: 250.00mg
Price: $25
Updated: 2026/05/18

Matrix Scientific

Product number: 131905
Product name: 2-(1H-Imidazol-2-yl)pyrazine
Packaging: 1.00g
Price: $96
Updated: 2026/05/18

Matrix Scientific

Product number: 131905
Product name: 2-(1H-Imidazol-2-yl)pyrazine
Packaging: 5.00g
Price: $481
Updated: 2026/05/18

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2-(1H-IMIDAZOL-2-YL)-PYRAZINE Chemical Properties,Usage,Production

Synthesis

19847-12-2

645-36-3

119165-68-3

Step 1: Synthesis of 2-(1H-imidazol-2-yl)pyrazine 2,2-Diethoxyethylamine (3 g, 2.25 mmol) was dissolved in anhydrous methanol (20 mL). To this solution was added sodium methanol (1.22 g, 22.5 mmol, as a 25% methanol solution). After stirring for 25 minutes at room temperature, pyrazine-2-carbonitrile (2.37 g, 22.5 mmol) and acetic acid (1.35 g, 22.5 mmol) were added sequentially, followed by stirring of the reaction mixture at 50 °C for 1 hour. Upon completion of the reaction, methanol (40 mL) and 6N hydrochloric acid (12 mL) were added and the reaction mixture was stirred overnight under reflux conditions. After cooling the reaction mixture to room temperature, the layers were separated by partitioning with 1:1 ether and water (60 mL). The aqueous layer was alkalized to pH 9-10 and extracted with a dichloromethane solution of 10% methanol. The organic extracts were combined, dried with magnesium sulfate, filtered and concentrated to afford the target compound 2-(1H-imidazol-2-yl)pyrazine (1.49 g, yellow solid). 1H NMR (400 MHz, MeOH-d4) δ ppm: 7.67 (s, 1H), 7.09 (d, J = 1.8 Hz, 1H), 6.99 (d, J = 2.5 Hz, 1H), 5.72 (s, 2H).

References

[1] Patent: WO2012/93148, 2012, A1. Location in patent: Page/Page column 36-37
[2] Patent: US2014/11802, 2014, A1. Location in patent: Paragraph 0196; 0197

2-(1H-IMIDAZOL-2-YL)-PYRAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(1H-IMIDAZOL-2-YL)-PYRAZINE Suppliers

China 41 India 1 United States 6 Global 48

Pure Chemistry Scientific Inc.

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119165-68-3, 2-(1H-IMIDAZOL-2-YL)-PYRAZINERelated Search:

Pyrazinamide 5-METHYL-2-(5-METHYL-PYRAZIN-2-YL)-3H-IMIDAZOLE-4-CARBOXYLIC ACID ETHYL ESTER RARECHEM BG FB 0033 2-pyrazin-2-yl-1H-benzimidazol-5-amine 2-(1H-IMIDAZOL-2-YL)-PYRAZINE 5-METHYL-2-(5-METHYL-PYRAZIN-2-YL)-3H-IMIDAZOLE-4-CARBOXYLIC ACID 2-(5-methylpyrazin-2-yl)-1H-benzimidazol-5-amine

2-(1H-IMIDAZOL-2-YL)-PYRAZINE

2-(1H-2-IMidazolyl)pyrazine

Pyrazine, 2-(1H-imidazol-2-yl)-

119165-68-3