6-FLUORO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE

Product Name: 6-FLUORO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE
CAS No.: 105655-00-3
Chemical Name: 6-FLUORO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE
Synonyms: 6-Fluoro-3,4-dihydro-2H-benzo[1,4]oxazine;2H-1,4-Benzoxazine, 6-fluoro-3,4-dihydro-;6-Fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazine;6-fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazine hydr;6-Fluoro-3,4-dihydro-2H-benzo[1,4]oxazine 1HCl salt;6-FLUORO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE;2-(2-fluorocyclohex-2-en-1-yl)-2H-oxazine hydrochloride;6-fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazine hydrochloride
CBNumber: CB9842076
Molecular Formula: C8H8FNO
Formula Weight: 153.15
MOL File: 105655-00-3.mol

More

Less

6-FLUORO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE Property

storage temp.: 2-8°C(protect from light)

More

Less

Safety

HS Code: 2934999090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: F595253
Product name: 6-Fluoro-3,4-dihydro-2h-benzo[1,4]oxazine
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: PC201013
Product name: 6-Fluoro-3,4-dihydro-2H-benzo[1,4]oxazine
Purity: 97%
Packaging: 250mg
Price: $58
Updated: 2021/12/16

Matrix Scientific

Product number: 073069
Product name: 6-Fluoro-3,4-dihydro-2H-benzo[1,4]oxazine
Purity: 95+%
Packaging: 250mg
Price: $125
Updated: 2021/12/16

Apolloscientific

Product number: PC201013
Product name: 6-Fluoro-3,4-dihydro-2H-benzo[1,4]oxazine
Purity: 97%
Packaging: 1g
Price: $145
Updated: 2021/12/16

Matrix Scientific

Product number: 073069
Product name: 6-Fluoro-3,4-dihydro-2H-benzo[1,4]oxazine
Purity: 95+%
Packaging: 1g
Price: $300
Updated: 2021/12/16

More

Less

6-FLUORO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE Chemical Properties,Usage,Production

Synthesis

398-63-0

105655-00-3

General procedure: Intermediate 13: Synthesis of 6-fluoro-3,4-dihydro-2H-benzo[1,4]oxazine To a stirred mixture of 6-fluoro-2H-benzo[b][1,4]oxazin-3(4H)-one (0.9 g, 5.3 mmol) in THF (23 mL) was added dropwise a THF solution of lithium aluminum hydride (6.5 mL, 1 M) at 0 °C to -5 °C. The reaction mixture was stirred for 2 h at room temperature. Subsequently, the mixture was carefully poured onto ice and extracted with ethyl acetate. The organic phase was dried with anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent. The residue was ground with ether to give 6-fluoro-3,4-dihydro-2H-benzo[1,4]oxazine (0.5 g, 61% yield) as a dark brown solid. NMR (d6-DMSO) δ: 3.25 (2H, m), 4.05 (2H, m), 6.03 (1H, br s), 6.17 (1H, dt), 6.31 (1H, dd), 6.57 (1H, dd).

References

[1] Archiv der Pharmazie, 2018, vol. 351, # 5,
[2] Patent: WO2011/144578, 2011, A1. Location in patent: Page/Page column 32; 33
[3] Patent: US2008/305169, 2008, A1
[4] Patent: EP2172453, 2010, A1. Location in patent: Page/Page column 14
[5] Patent: US2007/10670, 2007, A1. Location in patent: Page/Page column 94

6-FLUORO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

6-FLUORO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE Suppliers

China 39 Germany 1 India 2 United States 6 Global 48

Jinan Trio PharmaTech Co., Ltd.

Tel: 0531-88811783
Fax: +86 (531) 55696010 QQ 1762738062
Email: sales@trio-pharmatech.com
Country: China
ProdList: 1856
Advantage: 62

Shanghai Synthfine Chemical Co.,Ltd

Tel: 15921303235
Fax: QQ489466966
Email: sales@synthfine.com
Country: China
ProdList: 1041
Advantage: 58

NovoChemy Ltd.

Tel: 021-31261262/ 49 (0)17662837245
Fax: (0)21-33250524
Email: sales@novochemy.com
Country: Germany
ProdList: 6328
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Zhengzhou HSH Science & Technology Co., Ltd.

Tel: 0371-55932928 18937192232
Fax: 0086-0371-55932928
Email: 1282296214@qq.com
Country: China
ProdList: 498
Advantage: 55

Shanghai ChriChem Co., Ltd.

Tel: 021-54880687
Fax: 021-54880687
Country: China
ProdList: 511
Advantage: 55

ShangHai AmK Pharmaceutical Technology Co., Ltd.

Tel: 微信 17321281695 18019252918
Fax: 17321281695
Email: sale@amkchem.com
Country: China
ProdList: 15136
Advantage: 55

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

105655-00-3, 6-FLUORO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDERelated Search:

6-Fluoro-3,4-dihydro-1,8-naphthyridin-2(1H)-one 6,8-DIFLUORO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE ETHYL 6-FLUORO-3,4-DIHYDRO-2H-1,4-BENZOXAZINE-2-CARBOXYLATE BUTTPARK 120\07-80 6-FLUORO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE 6-FLUORO-2-METHYL-2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE 6-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE

6-fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazine hydr

6-FLUORO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE

6-Fluoro-3,4-dihydro-2H-benzo[1,4]oxazine

6-Fluoro-3,4-dihydro-2H-benzo[1,4]oxazine 1HCl salt

2-(2-fluorocyclohex-2-en-1-yl)-2H-oxazine hydrochloride

6-fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazine hydrochloride

6-Fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazine

2H-1,4-Benzoxazine, 6-fluoro-3,4-dihydro-

105655-00-3

1210274-51-0