ChemicalBook > CAS DataBase List > Palmitic acid ethyl ester

Palmitic acid ethyl ester

Product Name
Palmitic acid ethyl ester
CAS No.
628-97-7
Chemical Name
Palmitic acid ethyl ester
Synonyms
ETHYL PALMITATE;ETHYL HEXADECANOATE;HEXADECANOIC ACID ETHYL ESTER;Hexadecanoic acid ethyl;FEMA 2451;Ethyl palmita;Ethyl Hexadecanoate(C16:0);NSC 8918;Palmitic aci;Sixteen ethyl
CBNumber
CB9854033
Molecular Formula
C18H36O2
Formula Weight
284.48
MOL File
628-97-7.mol
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Palmitic acid ethyl ester Property

Melting point:
24-26 °C (lit.)
Boiling point:
192-193 °C/10 mmHg (lit.)
Density 
0.857 g/mL at 25 °C (lit.)
vapor pressure 
0.01Pa at 25℃
refractive index 
n20/D 1.440(lit.)
FEMA 
2451 | ETHYL PALMITATE
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
<24°C Solid,>26°C Liquid
Specific Gravity
0.857
color 
Colourless to Off-White
Odor
at 100.00 %. mild waxy fruity creamy milky balsamic greasy oily
Odor Type
waxy
biological source
synthetic
Water Solubility 
IMMISCIBLE
JECFA Number
39
BRN 
1782663
Dielectric constant
2.7（103℃）
LogP
7.74
CAS DataBase Reference
628-97-7(CAS DataBase Reference)
NIST Chemistry Reference
Hexadecanoic acid, ethyl ester(628-97-7)
EPA Substance Registry System
Hexadecanoic acid, ethyl ester (628-97-7)
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Safety

Hazard Codes 
Xi
Safety Statements 
23-24/25
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29157020
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H413May cause long lasting harmful effects to aquatic life

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W245100
Product name
Ethyl Palmitate
Purity
≥95%, FG
Packaging
1kg
Price
$284
Updated
2024/03/01
Sigma-Aldrich
Product number
W245100
Product name
Ethyl Palmitate
Purity
≥95%, FG
Packaging
5kg
Price
$483
Updated
2024/03/01
Sigma-Aldrich
Product number
W245100
Product name
Ethyl Palmitate
Purity
≥95%, FG
Packaging
10Kg
Price
$824
Updated
2024/03/01
Sigma-Aldrich
Product number
8.18775
Product name
Ethyl palmitate
Purity
for synthesis
Packaging
5ml
Price
$32.6
Updated
2024/03/01
Sigma-Aldrich
Product number
8.18775
Product name
Ethyl palmitate
Purity
for synthesis
Packaging
250ML
Price
$136
Updated
2024/03/01
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Palmitic acid ethyl ester Chemical Properties,Usage,Production

Description

Palmitic acid ethyl ester, also known as ethyl palmitate, it the ethyl ester form of palmitic acid. It can be used as a hair- and skin-conditioning agent. It has been shown that the combination between palmitic acid ethyl ester and cobra venom factor can enhance the survival of heterologous erythrocyte. Recent study has also demonstrated the potential anti-inflammatory activity of palmitic acid ethyl ester in several animal models.

Chemical Properties

clear colorless oily liquid after melting

Chemical Properties

Ethyl palmitate has a mild, waxy sweet odor. It is nearly tasteless and has a creamy mouthfeel.

Occurrence

Reported found in mutton, rye bread, rice, bourbon, vanilla, red sage, lemon balm, bilberry, Parmesan cheese, maple syrup, Jamaican rum, whiskey, grape wine, cognac, cocoa, green tea, mango, corn oil and mastic gum leaf oil.

Uses

Ethyl palmitate acts as a lubricant on the skin?s surfaces in order to get a soft and smooth appearance. It increases cytosolic Ca2+ concentration leading to pancreatic acinar cell injury due to excessive consumption of ethanol.

Uses

A fatty acid found in Amaranth oil; it shows inhibitory activity.

Definition

ChEBI: Ethyl hexadecanoate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of palmitic acid with the hydroxy group of ethanol. It has a role as a plant metabolite. It is a hexadecanoate ester and a long-chain fatty acid ethyl ester.

Aroma threshold values

Detection: 2 ppm

Taste threshold values

Taste characteristics at 30 ppm: waxy, fruity, creamy and fermented with a vanilla, balsamic nuance.

Synthesis Reference(s)

Tetrahedron, 48, p. 8775, 1992 DOI: 10.1016/S0040-4020(01)89450-3

General Description

Ethyl palmitate is a one of the major volatile compounds found in cooked rice and Luzhou-flavor raw liquor. It occurs naturally in licorice root and chamomile.

Safety

Palmitic acid ethyl ester, also known as Ethyl palmitate, is a versatile aromatic ester compound widely used as a food additive, fragrance ingredient and cosmetic emollient. Due to the lack of conclusive animal or human evidence, the substance is not classified as "harmful by ingestion". After ingestion, the substance may still harm personal health, especially if there is already significant damage to organs (such as liver, kidneys). Gastrointestinal discomfort may cause nausea and vomiting. However, in an occupational environment, unintentional ingestion is not considered a cause for concern. The Cosmetic Ingredient Safety Panel has evaluated the safety of palmitic acid esters. The panel evaluated the scientific data and concluded that ethylhexyl palmitate, cetyl palmitate and isopropyl palmitate are safe as cosmetic ingredients.

Synthesis

Synthesized by immobilized lipase-catalyzed alcoholysis and esterification in organic solvents.

References

Beste, Russell D, and R. D. Hamlin. "Skin permeation enhancer compositions comprising a monoglyceride and ethyl palmitate." US, US6267984. 2001.
Castro, O, et al. "Mechanism of ethyl palmitate and cobra venom factor enhancement of heterologous erythrocyte survival. " Proceedings of the Society for Experimental Biology & Medicine Society for Experimental Biology & Medicine 147.1(1974):106.
Saeed, N. M., et al. "Anti-inflammatory activity of methyl palmitate and ethyl palmitate in different experimental rat models. " Toxicology & Applied Pharmacology 264.1(2012):84-93.

Palmitic acid ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Palmitic acid ethyl ester manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Palmitic acid ethyl ester 628-97-7
Price
US $99.00-35.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-17
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Larch Arabinogalactan 628-97-7
Price
US $99.00-35.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-17
Hebei Mujin Biotechnology Co.,Ltd
Product
Palmitic acid ethyl ester 628-97-7
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-27

628-97-7, Palmitic acid ethyl esterRelated Search:

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  • Carbonyl Compounds
  • C12 to C63
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