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(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate

Product Name
(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
CAS No.
201856-57-7
Chemical Name
(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
Synonyms
Docetaxel Impurity 48;Docetaxel Impurity 54;Docetaxel Intermediate I;SIDE CHAINS OF DOCETAXEL--1;(3R,4S)-3-(1-ethoxyethoxy)-4-phenyl-N-Boc-2-azetidinone;(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidin...;(3R,4S)-1-t-butoxycarbonyl-3-(2-ethoxyethoxyl)-4-phenyl-2-azetidinone;(3R,4S)-1-T-BUTOXYCARBONYL-3-(2-ETHOXYETHOXYL)-4-PHENYL-2-AZETIDINONE,98+%;(3R, 4S) -1-tert butoxycarbonyl-3- (2-ethoxyethoxy) -4-phenyl-2-propanolam;(3r,4s)-tert-butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
CBNumber
CB9855065
Molecular Formula
C18H25NO5
Formula Weight
335.39
MOL File
201856-57-7.mol
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(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate Property

Boiling point:
459.6±45.0 °C(Predicted)
Density 
1.16
storage temp. 
2-8°C
pka
-4.97±0.60(Predicted)
CAS DataBase Reference
201856-57-7(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
E678310
Product name
(3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylicAcid1,1-DimethylethylEster
Packaging
100mg
Price
$195
Updated
2021/12/16
TRC
Product number
E678310
Product name
(3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylicAcid1,1-DimethylethylEster
Packaging
1g
Price
$1540
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
APN0000607
Product name
(3R,4S)-1-TERT-BUTOXYCARBONYL-3-(1-ETHOXYETHOXY)-4-PHENYL-2-AZETIDINONE
Purity
95.00%
Packaging
1G
Price
$1022.7
Updated
2021/12/16
Chemenu
Product number
CM200369
Product name
(3R,4S)-tert-Butyl3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
Purity
95%
Packaging
1g
Price
$408
Updated
2021/12/16
Alichem
Product number
201856577
Product name
(3R,4S)-tert-Butyl3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
Packaging
1g
Price
$427.28
Updated
2021/12/16
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(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate Chemical Properties,Usage,Production

Uses

(3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is used as a reagent in the synthesis of abeo-taxane derivatives that possess broad inhibitory effects against proliferation of colon cancer, melanoma, and renal cancer cell lines. (3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is also used as a reagent in the synthesis of a novel D-ring modified Docetaxel (D494420) analogue which has proven to have equipotent cytotoxicity in relation to Paclitaxel (P132500) towards cancer cell lines.

(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate Suppliers

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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China
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View Lastest Price from (3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate manufacturers

Longyan Tianhua Biological Technology Co., Ltd
Product
(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate 201856-57-7
Price
US $55.00/KG
Min. Order
1KG
Purity
99
Supply Ability
1000KG
Release date
2020-11-16
Career Henan Chemical Co
Product
(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate 201856-57-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-03

201856-57-7, (3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylateRelated Search:


  • 3-(1-ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid tert-butyl ester
  • Docetaxel Impurity 48
  • 3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-dimethylethyl ester
  • (3r,4s)-tert-butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
  • (3R,4S)-1-AZETIDINECARBOXYLIC ACID-3-(2-ETHOXYETHOXY)-4-PHENYL-2-PHENYL-AZETIDIONE
  • (3R,4S)-1-t-butoxycarbonyl-3-(2-ethoxyethoxyl)-4-phenyl-2-azetidinone
  • (3R,4S)-1-T-BUTOXYCARBONYL-3-(2-ETHOXYETHOXYL)-4-PHENYL-2-AZETIDINONE,98+%
  • SIDE CHAINS OF DOCETAXEL--1
  • (1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-dimethyl ethyl ester
  • Docetaxel Intermediate I
  • (3R,4S)-3-(1-ethoxyethoxy)-4-phenyl-N-Boc-2-azetidinone
  • tert-butyl (3R,4S)-3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
  • (3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic Acid 1,1-DiMethylethyl Ester
  • 1-Azetidinecarboxylic acid, 3-(1-ethoxyethoxy)-2-oxo-4-phenyl-, 1,1-dimethylethyl ester, (3R,4S)-
  • Docetaxel Impurity 54
  • (3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidin...
  • (3R, 4S) -1-tert butoxycarbonyl-3- (2-ethoxyethoxy) -4-phenyl-2-propanolam
  • 201856-57-7