(S)-2-(4-Fluorophenyl)pyrrolidine

Product Name: (S)-2-(4-Fluorophenyl)pyrrolidine
CAS No.: 298690-90-1
Chemical Name: (S)-2-(4-Fluorophenyl)pyrrolidine
Synonyms: (S)-2-(4-Fluorophenyl)pyrrolidine;(2S)-2-(4-fluorophenyl)pyrrolidine;Pyrrolidine, 2-(4-fluorophenyl)-, (2S)-;(S)-2-(4-Fluorophenyl)pyrrolidine (S)-2-(4-Fluorophenyl)pyrrolidine
CBNumber: CB9875223
Molecular Formula: C10H12FN
Formula Weight: 165.21
MOL File: 298690-90-1.mol

More

Less

(S)-2-(4-Fluorophenyl)pyrrolidine Property

Boiling point:: 235.5±33.0 °C(Predicted)
Density: 1.078±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 9.76±0.10(Predicted)
CAS DataBase Reference: 298690-90-1(CAS DataBase Reference)

More

Less

Safety

HS Code: 2933998090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: F791780
Product name: (S)-2-(4-Fluorophenyl)pyrrolidine
Packaging: 5mg
Price: $45
Updated: 2021/12/16

TRC

Product number: F791780
Product name: (S)-2-(4-Fluorophenyl)pyrrolidine
Packaging: 50mg
Price: $220
Updated: 2021/12/16

Apolloscientific

Product number: PC201224
Product name: (S)-2-(4-Fluorophenyl)pyrrolidine
Purity: 98%
Packaging: 250mg
Price: $344
Updated: 2021/12/16

Activate Scientific

Product number: AS7889
Product name: (S)-2-(4-Fluorophenyl)pyrrolidine
Purity: 95+% ee
Packaging: 1g
Price: $849
Updated: 2021/12/16

Apolloscientific

Product number: PC201224
Product name: (S)-2-(4-Fluorophenyl)pyrrolidine
Purity: 98%
Packaging: 1g
Price: $857
Updated: 2021/12/16

More

Less

(S)-2-(4-Fluorophenyl)pyrrolidine Chemical Properties,Usage,Production

Uses

(S)-2-(4-Fluorophenyl)pyrrolidine is a pyrrole compound and can be used in the synthesis of organic compounds.

Application

(S)-2-(4-Fluorophenyl)pyrrolidine, also known as amide 2-(4-fluorophenyl)-2-pyrrolidinone, is a drug that has been discovered but not yet clinically developed. It is a blocker of the atrial natriuretic peptide receptor.

Synthesis

The mixture of tert-butyl (4-(4-fluorophenyl)-4-oxobutyl)carbamate (0.2 mmol) and trifluoroacetic acid (equiv) in CH2Cl2 was stirred under nitrogen for 3 h. After all the acid and solvent had been removed under vacuum, the obtained substance was transferred to a nitrogen-filled glovebox and dissolved in a mixed solvent of toluene/THF (5:1, 1 mL). Ti(OiPr)4 (0.24 mmol), DABCO (0.04 mmol), Ir-L9 (0.002 mmol) and KI (0.04 mmol) were added subsequently to the above solution. The total solution was made to 3.0 mL. The resulting vial was transferred to an autoclave, which was charged with 50 atm of H2, and stirred at 50 °C for 13 h. The solution was quenched with aqueous sodium bicarbonate solution. The organic phase was concentratedand the metal complex was removed by using a short silica plug to give the (S)-2-(4-Fluorophenyl)pyrrolidine.

(S)-2-(4-Fluorophenyl)pyrrolidine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(S)-2-(4-Fluorophenyl)pyrrolidine Suppliers

China 58 India 2 United States 9 Global 69

Tianjin Xinghan Biotechnology Co., Ltd

Tel: 13230698506 18698089028
Email: 1725517238@qq.com
Country: China
ProdList: 5009
Advantage: 58

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Shijiazhuang Lickon PharmaTech Co., Ltd.

Tel: 031185291771 13832391721
Fax: 0311-67305698
Email: yaofeng2005@163.com
Country: China
ProdList: 975
Advantage: 58

Hygeia (Chengdu) pharmaceutical technique Co., Ltd

Tel: 028-84502008 13568869383
Fax: 028-66476329
Email: sales@hygeiapharm.com
Country: China
ProdList: 299
Advantage: 55

LABTER PHARMATECH(BEIJING) CO.,LTD

Tel: 010-56330744 18310155299
Fax: 010-56330744
Email: sales@labter.com.cn
Country: China
ProdList: 23957
Advantage: 55

Shanghai DongYang Biotechnology Co., Ltd.

Tel: 18657622632
Fax: -
Email: chemsharker@126.com
Country: China
ProdList: 371
Advantage: 55

Shanghai Chiral bio-compound co., Ltd.

Tel: 021-5068 3667/17749785980/1029026415; 17749785980
Fax: 021-50683667
Email: 1029026415@qq.com
Country: China
ProdList: 3013
Advantage: 58

Chongqing Acemol Technology Co.,Ltd

Tel: 023-86822659，企业QQ3004125759 18611316925
Email: sales@acemol.com
Country: China
ProdList: 995
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Nanjing Peptide Biotech Ltd.

Tel: 025-025-58361106-805-805 13082558573
Fax: 025-58361106-806
Email: liugang@njpeptide.com
Country: China
ProdList: 9980
Advantage: 55

298690-90-1, (S)-2-(4-Fluorophenyl)pyrrolidineRelated Search:

N-Methyl-2-pyrrolidone Polyvinylpyrrolidone N-Vinyl-2-pyrrolidone Povidone iodine Pyrrolidine METHYL-2-PYRROLIDONE 2-(3-Fluorophenyl)-pyrrolidine (3S,4R)-4-(2-FLUOROPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID 2-(2-FLUOROPHENYL)PYRROLIDINE 2-(2,4-DIFLUORO-PHENYL)-PYRROLIDINE (R)-2-(3-Fluorophenyl)pyrrolidine 3-(3-FLUOROPHENYL)PYRROLIDINE (S)-2-(3-Fluorophenyl)pyrrolidine (3S,4R)-4-(3-FLUOROPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID (3S,4R)-4-(4-FLUOROPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID ((3R,4S)-4-(3-FLUOROPHENYL)PYRROLIDIN-3-YL)METHANOL 3-(4-FLUORO-PHENYL)-PYRROLIDINE (R)-2-(4-Fluorophenyl)pyrrolidine

(2S)-2-(4-fluorophenyl)pyrrolidine

(S)-2-(4-Fluorophenyl)pyrrolidine (S)-2-(4-Fluorophenyl)pyrrolidine

(S)-2-(4-Fluorophenyl)pyrrolidine

Pyrrolidine, 2-(4-fluorophenyl)-, (2S)-

298690-90-1