acediasulfone sodium
- Product Name
- acediasulfone sodium
- CAS No.
- 127-60-6
- Chemical Name
- acediasulfone sodium
- Synonyms
- acediasulfone sodium;acediasulfone sodium USP/EP/BP;N-[4-[(4-Aminophenyl)sulfonyl]phenyl]glycine sodium salt
- CBNumber
- CB9881824
- Molecular Formula
- C14H15N2NaO4S
- Formula Weight
- 330.33
- MOL File
- 127-60-6.mol
acediasulfone sodium Chemical Properties,Usage,Production
Originator
Solfone ,Bracco
Manufacturing Process
24.8 g of 4,4'-diaminodiphenyl sulfone, 150 g of methyl chloroacetate and 150
ml of ethanol are refluxed together and refluxed for 24 hours. The alcohol and
excess methyl chloroacetate are then distilled off on a steam bath under
reduced pressure. The residue consisting of the hydrochloride salt of 4-amino-
4'-(carbomethoxymethylamino)diphenyl sulfone is mixed with of alcoholic
solution containing 2.5 g lithium hydroxide and refluxed for 4 hours on the
steam bath. Most of the alcohol is removed by distillation and the residual
lithium salt of 4-amino-4'-(carboxymethylamino)diphenyl sulfone taken up
water. The solution is filtered and dilute HCl added until no more separation
occurs. The 4-amino-4'-(carboxymethylamino)diphenyl sulfone thus obtained
is collected and dried.
The sodium salt of 4-amino-4'-(carboxymethylamino)diphenyl sulfone is
prepared by dissolving the free acid in an aqueous solution containing one
equivalent of sodium hydroxide and evaporating the solution to dryness in
vacuo.
Therapeutic Function
Antibacterial
acediasulfone sodium Preparation Products And Raw materials
Raw materials
Preparation Products
acediasulfone sodium Suppliers
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- China
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View Lastest Price from acediasulfone sodium manufacturers
- Product
- acediasulfone sodium 127-60-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-07-16