ChemicalBook > CAS DataBase List > 7-chloro-1H-indole-2-carboxylic acid

7-chloro-1H-indole-2-carboxylic acid

Product Name
7-chloro-1H-indole-2-carboxylic acid
CAS No.
28899-75-4
Chemical Name
7-chloro-1H-indole-2-carboxylic acid
Synonyms
7-Chloroindole-2-carboxylic acid;1H-Indole-2-carboxylic acid, 7-chloro-;7-chloro-1H-indole-2-carboxylic acid(SALTDATA: FREE)
CBNumber
CB9895577
Molecular Formula
C9H6ClNO2
Formula Weight
195.6
MOL File
28899-75-4.mol
More
Less

7-chloro-1H-indole-2-carboxylic acid Property

Boiling point:
449.7±25.0 °C(Predicted)
Density 
1.548±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
4.23±0.30(Predicted)
InChI
InChI=1S/C9H6ClNO2/c10-6-3-1-2-5-4-7(9(12)13)11-8(5)6/h1-4,11H,(H,12,13)
InChIKey
NVKAHBFPKVINGE-UHFFFAOYSA-N
SMILES
N1C2=C(C=CC=C2Cl)C=C1C(O)=O
More
Less

Safety

HazardClass 
IRRITANT
HS Code 
2933998090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TRC
Product number
C367613
Product name
7-Chloro-1H-indole-2-carboxylicacid
Packaging
100mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC116393
Product name
7-Chloro-1H-indole-2-carboxylic acid
Packaging
250mg
Price
$57.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC116393
Product name
7-Chloro-1H-indole-2-carboxylic acid
Packaging
500mg
Price
$100
Updated
2021/12/16
Matrix Scientific
Product number
036837
Product name
7-Chloro-1H-indole-2-carboxylic acid
Packaging
500mg
Price
$126
Updated
2021/12/16
Apolloscientific
Product number
OR906974
Product name
7-Chloro-1H-indole-2-carboxylicacid
Purity
97%
Packaging
5g
Price
$495
Updated
2021/12/16
More
Less

7-chloro-1H-indole-2-carboxylic acid Chemical Properties,Usage,Production

Uses

7-chloro-1H-indole-2-carboxylic acid is an important pharmaceutical intermediate compound used in the preparation of protease inhibitors.

Synthesis

A mixture of 111.5 g of 7-chloroindole-2-carboxylate in 31.25 g of 96percent sodium hydroxide in 183 ml of methanol and 183 ml of water were heated under reflux for 1 hour, cooled to 45 ° C, and 10 percent hydrochloric acid was added dropwise to a pH of 3 to 4. The mixture was sufficiently cooled to obtain 89.7 g of product as an off-white 7-chloro-1H-indole-2-carboxylic acid.

7-chloro-1H-indole-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

7-chloro-1H-indole-2-carboxylic acid Suppliers

Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
More
Less

View Lastest Price from 7-chloro-1H-indole-2-carboxylic acid manufacturers

SHANDONG OUCHEM CO.,LTD.
Product
7-chloro-1H-indole-2-carboxylic acid 28899-75-4
Price
US $0.00-0.00/kg
Min. Order
0.1kg
Purity
98% Min.
Supply Ability
200
Release date
2024-01-17