ChemicalBook > CAS DataBase List > (±)-alpha-[[isopropylamino]methyl]-4-nitrobenzyl alcohol monohydrochloride
(±)-alpha-[[isopropylamino]methyl]-4-nitrobenzyl alcohol monohydrochloride
- Product Name
- (±)-alpha-[[isopropylamino]methyl]-4-nitrobenzyl alcohol monohydrochloride
- CAS No.
- 5704-60-9
- Chemical Name
- (±)-alpha-[[isopropylamino]methyl]-4-nitrobenzyl alcohol monohydrochloride
- Synonyms
- INPEA;Nifenalol (hydrochloride);Nifenalol monohydrochloride;nifenalol.HCl, 10 mM in DMSO;2-(Isopropylamino)-1-(p-nitrophenyl)ethanol hydrochloride;1-(4-Nitrophenyl)-1-hydroxy-2-isopropylaminoethane hydrochloride;()-alpha-[[isopropylamino]methyl]-4-nitrobenzylalcoholmonohydrochloride;(±)-alpha-[[isopropylamino]methyl]-4-nitrobenzyl alcohol monohydrochloride;(±)-alpha-[[isopropylamino]methyl]-4-nitrobenzyl alcohol monohydrochloride;Benzenemethanol, α-[[(1-methylethyl)amino]methyl]-4-nitro-, monohydrochloride
- CBNumber
- CB9908156
- Molecular Formula
- C11H16N2O3.ClH
- Formula Weight
- 260.72
- MOL File
- 5704-60-9.mol
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(±)-alpha-[[isopropylamino]methyl]-4-nitrobenzyl alcohol monohydrochloride Property
- Melting point:
- 181°
- storage temp.
- -20°C
- solubility
- DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 5 mg/ml,PBS (pH 7.2): 10 mg/ml
- form
- A crystalline solid
- color
- White to off-white
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0017060
- Product name
- NIFENALOL HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.8
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC10114
- Product name
- Nifenalol
- Purity
- >98%
- Packaging
- 1g
- Price
- $1000
- Updated
- 2021/12/16
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(±)-alpha-[[isopropylamino]methyl]-4-nitrobenzyl alcohol monohydrochloride Chemical Properties,Usage,Production
Uses
Nifenalol hydrochloride is a β-adrenergic receptor antagonist. Nifenalol hydrochloride induces the Early Afterdepolarization (EAD) effect. EAD is a phenomenon in cardiac electrophysiology that usually occurs during an action potential in ventricular muscle cells and can lead to arrhythmia. The EAD effect of Nifenalol hydrochloride can be blocked by Tetrodotoxin. Nifenalol hydrochloride is used in the study of conditions such as irregular heartbeat or high blood pressure[1].
IC 50
β-adrenoceptor
References
[1] Lemmens-Gruber R, et al. Arrhythmogenic effect of beta-adrenoceptor-blocking drugs in Purkinje fibres of guinea-pig hearts. Arch Int Pharmacodyn Ther. 1996 Jan-Feb;331(1):46-58. PMID:8896710
(±)-alpha-[[isopropylamino]methyl]-4-nitrobenzyl alcohol monohydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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