ChemicalBook > CAS DataBase List > (+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride

Product Name
(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride
CAS No.
5843-53-8
Chemical Name
(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride
Synonyms
BA-7205;Rexigen;ClobenzorexHCl;Einecs 227-434-5;(S)-(+)-Clobenzorex Hydrochloride;N-(2-chlorobenzyl)-1-phenylpropan-2-amine hydrochloride;Chlorhydrate de D-N-(phenyl-1 propyl-2) chloro-2 benzylamine;(2-chlorobenzyl)-(1-methyl-2-phenyl-ethyl)amine hydrochloride;N-[(2-chlorophenyl)methyl]-1-phenylpropan-2-amine hydrochloride;(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride
CBNumber
CB9928091
Molecular Formula
C16H19Cl2N
Formula Weight
296.23476
MOL File
5843-53-8.mol
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(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Property

Melting point:
182-183° (isopropanol)
alpha 
D20 +26.3° (water)
solubility 
Methanol (Slightly), Water (Slightly, Heated)
form 
Solid
color 
White to Off-White
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Safety

Toxicity
LD50 i.p. in mice: 103 mg/kg (Boissier et al.)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FC131572
Product name
N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
Packaging
250mg
Price
$57.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC131572
Product name
N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
Packaging
500mg
Price
$100
Updated
2021/12/16
Matrix Scientific
Product number
155683
Product name
N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
Packaging
0.500g
Price
$160
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC131572
Product name
N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
Packaging
1g
Price
$170
Updated
2021/12/16
Matrix Scientific
Product number
155683
Product name
N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
Packaging
1g
Price
$200
Updated
2021/12/16
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(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Asenlix,Aventis

Uses

The S-enantiomer of Clobenzorex (C583000), an anorexic.

Manufacturing Process

A solution of 21.0 g (0.15 mol) of 2-chlorobenzaldehyde in 100 ml of ethanol (95%) was added to a solution of 20.5 g (0.152 mol) of D-1-phenyl-2-aminopropane in 100 ml of ethanol (95%). After standing for 15 h at room temperature, the ethanol was driven off, and the oily residue was then distilled to yield 36.2 g (94%) of D-N-(2-chlorobenzylidene)-2-amino-1- phenylpropane, boiling point 142°-146°C/0.1 mm Hg.
To the solution of 36.0 g (0.14 mol) of D-N-(2-chlorobenzylidene)-2-amino-1- phenylpropane in 200 ml of dry methanol were added, in portions, 5.3 g (0.14 mol) of sodium borohydride. The mixture was stirred for 1 h at room
temperature, and refluxed for 1 h water (100 ml) was then added and the methanol was removed in vacuo. After acidifying carefully with dilute hydrochloric acid, the solution was made alkaline by dilute sodium hydroxide, and extracted with ether. 33.0 g (90%) of D-N-(1-phenyl-2-propyl)-2-
chlorobenzylamine, boiling point 132°-134°C/0.1 mm Hg, were obtained by distillation.

Therapeutic Function

Anorexic

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Suppliers

Chizhou Kailong Import and Export Trade Co., Ltd.
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Fax
-
Email
xg01_gj@163.com
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China
ProdList
9503
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Angel Pharmatech, Ltd.
Tel
17317130613
Fax
QQ3358272972
Email
3358272972@qq.com
Country
China
ProdList
3244
Advantage
58
Alfa Chemistry
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+1-5166625404
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
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21317
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Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
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021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
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Hangzhou Taorui Biotechnology Co., Ltd
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4000-360-990 15268198094
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sales@torreybio.com
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China
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Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
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15229059051
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1027@dideu.com
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China
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9945
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Pushan Industry (Shaanxi) Co., Ltd.
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029-81310890 13571859809
Email
info@pushanshiye.com
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China
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10004
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LGC Science (Shanghai) Ltd.
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17717235263
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cindy.yang@lgcgroup.com
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China
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Shanghai Haohong Scientific Co., Ltd.
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400-400-8210725
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malulu@leyan.com
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China
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40041
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ATK CHEMICAL COMPANY LIMITED
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+undefined-21-51877795
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+86 21 5161 9052/ 5187 7796
Email
ivan@atkchemical.com
Country
China
ProdList
32686
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5843-53-8, (+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochlorideRelated Search:


  • BenzeneethanaMine,N-[(2-chlorophenyl)Methyl]-a-Methyl-, hydrochloride (1:1), (+)-
  • (2-chlorobenzyl)-(1-methyl-2-phenyl-ethyl)amine hydrochloride
  • N-(2-chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
  • BA-7205
  • Chlorhydrate de D-N-(phenyl-1 propyl-2) chloro-2 benzylamine
  • Chlorhydrate de D-N-(phenyl-1 propyl-2) chloro-2 benzylamine [french]
  • Einecs 227-434-5
  • (S)-(+)-Clobenzorex Hydrochloride
  • N-[(2-chlorophenyl)methyl]-1-phenyl-propan-2-amine hydrochloride
  • N-[(2-chlorophenyl)methyl]-1-phenylpropan-2-amine hydrochloride
  • Phenethylamine, N-(o-chlorobenzyl)-alpha-methyl-, hydrochloride, (+)-
  • Rexigen
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  • (2S)-N-[(2-chlorophenyl)methyl]-1-phenylpropan-2-amine:hydrochloride
  • ClobenzorexHCl
  • (+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride
  • 5843-53-8
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