(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride

Product Name: (+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride
CAS No.: 5843-53-8
Chemical Name: (+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride
Synonyms: BA-7205;Rexigen;ClobenzorexHCl;Einecs 227-434-5;(S)-(+)-Clobenzorex Hydrochloride;N-(2-chlorobenzyl)-1-phenylpropan-2-amine hydrochloride;Chlorhydrate de D-N-(phenyl-1 propyl-2) chloro-2 benzylamine;(2-chlorobenzyl)-(1-methyl-2-phenyl-ethyl)amine hydrochloride;N-[(2-chlorophenyl)methyl]-1-phenylpropan-2-amine hydrochloride;(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride
CBNumber: CB9928091
Molecular Formula: C16H19Cl2N
Formula Weight: 296.23476
MOL File: 5843-53-8.mol

More

Less

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Property

Melting point:: 182-183° (isopropanol)
alpha: D20 +26.3° (water)
solubility: Methanol (Slightly), Water (Slightly, Heated)
form: Solid
color: White to Off-White

More

Less

Safety

Toxicity: LD50 i.p. in mice: 103 mg/kg (Boissier et al.)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FC131572
Product name: N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
Packaging: 250mg
Price: $57.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC131572
Product name: N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
Packaging: 500mg
Price: $100
Updated: 2021/12/16

Matrix Scientific

Product number: 155683
Product name: N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
Packaging: 0.500g
Price: $160
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC131572
Product name: N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
Packaging: 1g
Price: $170
Updated: 2021/12/16

Matrix Scientific

Product number: 155683
Product name: N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
Packaging: 1g
Price: $200
Updated: 2021/12/16

More

Less

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Asenlix,Aventis

Uses

The S-enantiomer of Clobenzorex (C583000), an anorexic.

Manufacturing Process

A solution of 21.0 g (0.15 mol) of 2-chlorobenzaldehyde in 100 ml of ethanol (95%) was added to a solution of 20.5 g (0.152 mol) of D-1-phenyl-2-aminopropane in 100 ml of ethanol (95%). After standing for 15 h at room temperature, the ethanol was driven off, and the oily residue was then distilled to yield 36.2 g (94%) of D-N-(2-chlorobenzylidene)-2-amino-1- phenylpropane, boiling point 142°-146°C/0.1 mm Hg.
To the solution of 36.0 g (0.14 mol) of D-N-(2-chlorobenzylidene)-2-amino-1- phenylpropane in 200 ml of dry methanol were added, in portions, 5.3 g (0.14 mol) of sodium borohydride. The mixture was stirred for 1 h at room
temperature, and refluxed for 1 h water (100 ml) was then added and the methanol was removed in vacuo. After acidifying carefully with dilute hydrochloric acid, the solution was made alkaline by dilute sodium hydroxide, and extracted with ether. 33.0 g (90%) of D-N-(1-phenyl-2-propyl)-2-
chlorobenzylamine, boiling point 132°-134°C/0.1 mm Hg, were obtained by distillation.

Therapeutic Function

Anorexic

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Suppliers

Canada 1 China 15 Germany 1 India 2 United Kingdom 1 United States 2 Global 22

Chizhou Kailong Import and Export Trade Co., Ltd.

Tel
Fax: -
Email: xg01_gj@163.com
Country: China
ProdList: 9484
Advantage: 50

Shanghai SuperLan Chemcial Technique Centre

Tel: 021-2022843681 15618226720
Fax: +86-21-51601218
Email: lucy@atkchemical.com
Country: China
ProdList: 9952
Advantage: 58

Angel Pharmatech, Ltd.

Tel: 17317130613
Fax: QQ3358272972
Email: 3358272972@qq.com
Country: China
ProdList: 3253
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44458
Advantage: 58

Hangzhou Taorui Biotechnology Co., Ltd

Tel: 4000-360-990 15268198094
Email: sales@torreybio.com
Country: China
ProdList: 2885
Advantage: 58

Shaanxi DIDU pharmaceutical and Chemical Co., Ltd

Tel: 15229059051
Email: 1027@dideu.com
Country: China
ProdList: 10003
Advantage: 58

Pushan Industry (Shaanxi) Co., Ltd.

Tel: 029-81310890 13571859809
Email: info@pushanshiye.com
Country: China
ProdList: 10000
Advantage: 58

LGC Science (Shanghai) Ltd.

Tel: 17717235263
Email: cindy.yang@lgcgroup.com
Country: China
ProdList: 15583
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-400-8210725
Email: malulu@leyan.com
Country: China
ProdList: 39990
Advantage: 58

TLC Pharmaceutical Standards Ltd.

Tel: 18012923235
Email: chinasales04@tlcstandards.com.cn
Country: China
ProdList: 4916
Advantage: 58

5843-53-8, (+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochlorideRelated Search:

(2S)-2-[(2,4-dichlorobenzoyl)amino]-3-phenylpropanoic acid 2-(2-CHLORO-BENZYL)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID HYDROCHLORIDE 2-(2-CHLORO-BENZYL)-7-FLUORO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID HYDROCHLORIDE (3S)-3-BENZYL-4-(2,4-DICHLOROBENZOYL)-7-(METHYLSULFONYL)-3,4-DIHYDROQUINOXALIN-2(1H)-ONE 2,4-DICHLORO-N-(6-METHYL-4-OXO-3,4-DIHYDRO-2H-THIOCHROMEN-3-YL)BENZENECARBOXAMIDE 7-CHLORO-2-(2-CHLORO-BENZYL)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID HYDROCHLORIDE 2-(2-CHLORO-BENZYL)-7-TRIFLUOROMETHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID HYDROCHLORIDE OTAVA-BB BB7018611137 2-[(2,4-DICHLOROBENZOYL)AMINO]-3-PHENYLPROPANOIC ACID (+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride

BenzeneethanaMine,N-[(2-chlorophenyl)Methyl]-a-Methyl-, hydrochloride (1:1), (+)-

(2-chlorobenzyl)-(1-methyl-2-phenyl-ethyl)amine hydrochloride

N-(2-chlorobenzyl)-1-phenylpropan-2-amine hydrochloride

BA-7205

Chlorhydrate de D-N-(phenyl-1 propyl-2) chloro-2 benzylamine

Chlorhydrate de D-N-(phenyl-1 propyl-2) chloro-2 benzylamine [french]

Einecs 227-434-5

(S)-(+)-Clobenzorex Hydrochloride

N-[(2-chlorophenyl)methyl]-1-phenyl-propan-2-amine hydrochloride

N-[(2-chlorophenyl)methyl]-1-phenylpropan-2-amine hydrochloride

Phenethylamine, N-(o-chlorobenzyl)-alpha-methyl-, hydrochloride, (+)-

Rexigen

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride

(2S)-N-[(2-chlorophenyl)methyl]-1-phenylpropan-2-amine:hydrochloride

ClobenzorexHCl

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride

5843-53-8

Amines

Aromatics

Intermediates & Fine Chemicals

Pharmaceuticals