ChemicalBook > CAS DataBase List > 1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol

1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol

Product Name
1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol
CAS No.
29023-48-1
Chemical Name
1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol
Synonyms
rac-Timolol;Racemic timolol;rac Timolol-d5 Maleate;(+/-)-Timolol-d5 Maleate;1,2,5-Thiadiazole, 2-propanol deriv.;1-[(1,1-DiMethylethyl)aMino]-3-[[4-(4-Morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-;3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole-d5 Maleate;2-Propanol, 1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]- (8CI);1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol;2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]- (9CI)
CBNumber
CB9942242
Molecular Formula
C13H24N4O3S
Formula Weight
316.42
MOL File
29023-48-1.mol
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1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol Property

Melting point:
210-212°C
Boiling point:
487.2±45.0 °C(Predicted)
Density 
1.224±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
13.38±0.20(Predicted)
color 
White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
021871
Product name
rac Timolol-d5 Maleate
Packaging
1mg
Price
$446
Updated
2021/12/16
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1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Antihypertensive; antiarrhythmic (class II); antianginal; antiglaucoma agent

Uses

rac Timolol Maleate is an antihypertensive and antiarrhythmic. It can be used to treat hemangioma and vascular anomaly.

Definition

ChEBI: Timolol is 1,2,5-Thiadiazole substituted at the 3 position by a 3-(tert-butylamino)-2-hydroxypropoxy group and at the 4 position by a morpholin-4-yl group. The (S)-(-) enantiomer, also known as timolol, is a beta-adrenergic antagonist and is used in the mangement of glaucoma, hypertension, angina pectoris and myocardial infarction, and for the prevention of migraine. It is a member of thiadiazoles and a member of morpholines. It derives from a hydride of a 1,2,5-thiadiazole.

1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol Suppliers

J & K SCIENTIFIC LTD.
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29023-48-1, 1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol Related Search:


  • 1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol
  • 1,2,5-Thiadiazole, 2-propanol deriv.
  • 2-Propanol, 1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]- (8CI)
  • 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]- (9CI)
  • Racemic timolol
  • (+/-)-Timolol-d5 Maleate
  • 1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol-d5 Maleate
  • 3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole-d5 Maleate
  • rac Timolol-d5 Maleate
  • 1-[(1,1-DiMethylethyl)aMino]-3-[[4-(4-Morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-
  • rac-Timolol
  • 29023-48-1
  • C17H23D5N4O7S
  • Amines
  • Heterocycles
  • Isotope Labelled Compounds
  • Intermediates & Fine Chemicals
  • Isotope Labeled Compounds
  • Pharmaceuticals