GUANIDINYL NALTRINDOLE
- Product Name
- GUANIDINYL NALTRINDOLE
- CAS No.
- 219655-57-9
- Chemical Name
- GUANIDINYL NALTRINDOLE
- Synonyms
- 5'guanidinonaltrindole bis(trifluoroacetate);5'-Guanidinonaltrindole di(trifluoroacetate);5′-Guanidinonaltrindole di(trifluoroacetate) salt hydrate;5μ-Guanidinonaltrindole hydrate di(trifluoroacetate) salt
- CBNumber
- CB9973031
- Molecular Formula
- C27H29N5O3
- Formula Weight
- 471.558
- MOL File
- 219655-57-9.mol
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GUANIDINYL NALTRINDOLE Property
- storage temp.
- 2-8°C
- solubility
- H2O: soluble30mg/mL
- form
- solid
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- G3416
- Product name
- 5′-Guanidinonaltrindole di(trifluoroacetate) salt hydrate
- Purity
- solid, ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $395
- Updated
- 2024/03/01
TRC
- Product number
- G821700
- Product name
- 5′-Guanidinonaltrindole di(trifluoroacetate) salt hydrate
- Packaging
- 1mg
- Price
- $275
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- NUC0004605
- Product name
- GUANIDINYL NALTRINDOLE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.57
- Updated
- 2021/12/16
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GUANIDINYL NALTRINDOLE Chemical Properties,Usage,Production
Uses
5′-Guanidinonaltrindole di(trifluoroacetate) Salt is a selective opioid receptor antagonist. It has also been utilized to develop fluorescent methods to identify phosphopantetheinyl transferase inhibitors.
Uses
5′-Guanidinonaltrindole di(trifluoroacetate) salt hydrate (GNTI) has been used as a selective κ opioid receptor antagonist:
- to study the influence of opioid receptor types on the anti-hyperalgesic effect of dipeptidyl peptidase 4 (DPP4) inhibitors in inflammation
- to study the role of κ opioid receptor in the forebrain-dependent associative task, Whisker-Trace Eyeblink conditioning (WTEB)
- to validate its inhibitory actions on Akt kinase activities
Biochem/physiol Actions
5′-Guanidinonaltrindole di(trifluoroacetate) (GNTI) is a 5‘-guanidine derivative and a selective κ opiate receptor antagonist. It is five-fold more potent and 500-fold more selective than norbinaltorphimine (nor-BNI) for the κ opioid receptor in smooth muscle preparations.
GUANIDINYL NALTRINDOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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GUANIDINYL NALTRINDOLE Suppliers
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91
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