METHYL 4-AZA-5ALPHA-ANDROSTA-1-EN-3-ONE-17BETA-CARBOXYLATE Chemical Properties

Melting point:

280-282°C (dec.)

Boiling point:

478.6±45.0 °C(Predicted)

Density 

1.113±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,2-8°C

solubility 

Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)

form 

Solid

pka

14.15±0.70(Predicted)

color 

White to Off-White

InChIKey

WMSQGMYJYBSBKA-ALHYADCGSA-N

SMILES

N1[C@@]2([H])[C@@](C)([C@@]3([H])CC[C@@]4(C)[C@]([H])([C@]3([H])CC2)CC[C@@H]4C(OC)=O)C=CC1=O

METHYL 4-AZA-5ALPHA-ANDROSTA-1-EN-3-ONE-17BETA-CARBOXYLATE Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester (Finasteride EP Impurity B) is an impurity of Finasteride (F342000) and Dutasteride (D735000). An intermediate in the synthesis of Finasteride and Dutasteride, 5α-reductase inhibitors used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders. Finasteride impurity.

Uses

Finasteride (F342000) impurity. A novel intermediate in the synthesis of Finasteride, a 5α-reductase inhibitor used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders.

Uses

Finasteride (F342000) and Dutasteride (D735000) impurity. An intermediate in the synthesis of Finasteride and Dutasteride, 5α-reductase inhibitors used for treatment of benign prostatic hyperplasia ac ne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders.

METHYL 4-AZA-5ALPHA-ANDROSTA-1-EN-3-ONE-17BETA-CARBOXYLATE(103335-41-7)Related Product Information

• 4-Aza-5a-androstan-1-ene-3-one-17b-carboxylic acid
• Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate
• Dutasteride Chloro IMpurity
• Dutasteride Related Impurity 1
• Dutasteride EP Impurity I
• (4aR,4bS,6aS,7S,9aS,9bS,11aS)-4a,6a-diMethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid
• 5,6-Dehydro-17β-dutasteride
• 5β-Dutasteride
• Dutasteride IMpurity L
• Dutasteride Impurity E (Dutasteride 17-alfa-epimer)
• (5a,6a,17)-N-(1,1-Dimethylethyl)-6-hydroxy-3-oxo-4-azaandrost-1-ene-17-carboxamide
• 2,5-Bis(trifluoromethyl)aniline
• Dutasteride
• Dihydrodutasteride
• 2,6-BIS(TRIFLUOROMETHYL)ANILINE
• 3,4-Bis-trifluoromethyl-phenylamine
• 1,4-Bis(trifluoromethyl)-benzene
• JWJOTENAMICLJG-XHGXNVPLSA-N