Basic information Safety Supplier Related

2,4,6-Tribromo-3-hydroxybenzaldehyde

Basic information Safety Supplier Related

2,4,6-Tribromo-3-hydroxybenzaldehyde Basic information

Product Name:
2,4,6-Tribromo-3-hydroxybenzaldehyde
Synonyms:
  • 3-hydroxy-2,4,6-tribromo-benzaldehyd
  • 3-HYDROXY-2,4,6-TRIBROMOBENZALDEHYDE
  • 2,4,6-TRIBROMO-3-HYDROXYBENZALDEHYDE
  • Benzaldehyde, 2,4,6-tribromo-3-hydroxy-
  • Venadaparib Impurity 47
CAS:
2737-22-6
MF:
C7H3Br3O2
MW:
358.81
Product Categories:
  • Aromatic Aldehydes & Derivatives (substituted)
Mol File:
2737-22-6.mol
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2,4,6-Tribromo-3-hydroxybenzaldehyde Chemical Properties

Melting point:
120-122°C
Boiling point:
305.9±42.0 °C(Predicted)
Density 
2.423±0.06 g/cm3(Predicted)
storage temp. 
Store at 0-8 ℃
solubility 
soluble in Methanol
form 
powder to crystal
pka
5.62±0.28(Predicted)
color 
White to Almost white
Sensitive 
Air Sensitive
BRN 
2098037
CAS DataBase Reference
2737-22-6(CAS DataBase Reference)
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Safety Information

Risk Statements 
36/37/38
Safety Statements 
26-36
RTECS 
CU6900000
Toxicity
mouse,LD50,intravenous,56mg/kg (56mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#01793,

MSDS

  • Language:English Provider:ALFA
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2,4,6-Tribromo-3-hydroxybenzaldehyde Usage And Synthesis

Description

2,4,6-Tribromo-3-hydroxybenzaldehyde (2,4,6-TBHB) is an aldehyde that is synthesized from the reaction of 2,4,6-trichlorobenzaldehyde and bromine. It has been shown to be cytotoxic in tumour cell lines in vitro. This compound binds to DNA by covalent binding and inhibits the synthesis of proteins. 2,4,6-TBHB also inhibits cellular uptake of halides such as chloride and bromide ions. This aldehyde has been shown to induce cell death in human lung cancer cells in a concentration dependent manner.

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