Basic information Safety Supplier Related

20-ALPHA-DIHYDROCORTISOL

Basic information Safety Supplier Related

20-ALPHA-DIHYDROCORTISOL Basic information

Product Name:
20-ALPHA-DIHYDROCORTISOL
Synonyms:
  • REICHSTEIN'S SUBSTANCE 'EPI' 'E'
  • REICHSTEIN'S EPI ''E''
  • 20-ALPHA-DIHYDROCORTISOL
  • 4-PREGNEN-11-BETA, 17,20-ALPHA, 21-TETROL-3-ONE
  • 4-PREGNEN-11BETA,17ALPHA,20ALPHA,21-TETROL-3-ONE
  • 4-pregnene-11B,17A,20A,21-tetrol-3-one
  • 11B,17ALPHA,20ALPHA,21-Tetrahydroxy-4-pregnen-3-one
  • 20alpha-hydroxycortisol
CAS:
1719-79-5
MF:
C21H32O5
MW:
364.48
Mol File:
1719-79-5.mol
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20-ALPHA-DIHYDROCORTISOL Chemical Properties

Melting point:
250-252 °C
Boiling point:
586.6±50.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
pka
14.04±0.70(Predicted)
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20-ALPHA-DIHYDROCORTISOL Usage And Synthesis

Uses

20α-Dihydrocortisol is a metabolite of Cortisol (H714615) which is a topical corticosteroid (1), more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland (2). Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis (3); suppress the immune system; and aid in fat, protein and carbohydrate metabolism.

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