(S)-Modafinil
(S)-Modafinil Basic information
- Product Name:
- (S)-Modafinil
- Synonyms:
-
- (S)-(+)-Modafinil
- (S)-Modafinil
- 2-[(S)-(Diphenylmethyl)sulfinyl]acetamide
- CRL 40983
- AcetaMide, 2-[(S)- (diphenylMethyl)sulfinyl]-
- Acetamide,2-[(S)-(diphenylmethyl)sulfinyl]- (Related Reference)
- YFGHCGITMMYXAQ-IBGZPJMESA-N
- Modafinil S-Isomer
- CAS:
- 112111-47-4
- MF:
- C15H15NO2S
- MW:
- 273.35
- Product Categories:
-
- Chiral Reagents
- Intermediates & Fine Chemicals
- Neurochemicals
- Pharmaceuticals
- Mol File:
- 112111-47-4.mol
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(S)-Modafinil Chemical Properties
- Melting point:
- 157-159°C
- Boiling point:
- 559.1±50.0 °C(Predicted)
- Density
- 1.283±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMF: 25 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 0.25 mg/ml
- form
- A crystalline solid
- pka
- 14.88±0.40(Predicted)
- CAS DataBase Reference
- 112111-47-4
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(S)-Modafinil Usage And Synthesis
Chemical Properties
White Solid
Uses
Used for treatment of excessive sleepiness, α1-adrenoceptor agonist.
Uses
(S)-Modafinil is Used for treatment of excessive sleepiness, it is a1-adrenoceptor agonist.
Definition
ChEBI: (S)-modafinil is a 2-[(diphenylmethyl)sulfinyl]acetamide that has S configuration at the sulfur atom. The racemate comprising (S)-modafinil and its enantiomer, armodafinil, is known as modafinil and is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The enantiomers have similar pharmacological actions in animals. It has a role as a central nervous system stimulant and a eugeroic. It is an enantiomer of an armodafinil.