Levoprotiline Chemical Properties

Boiling point:

463.6±30.0 °C(Predicted)

Density 

1.152±0.06 g/cm3(Predicted)

pka

14.60±0.20(Predicted)

Levoprotiline Usage And Synthesis

Uses

R-(-)-Oxaprotiline (Levoprotiline) is an antidepressant with anticholinergic and sympathostimulatory activities. R-(-)-Oxaprotiline exhibits different abilities to block norepinephrine uptake and anticholinergic activity compared to its enantiomer C 49802 B-Ba. R-(-)-Oxaprotiline in human studies shows physiological effects consistent with those in animals. Administration of R-(-)-Oxaprotiline results in a modest increase in heart rate and arterial blood pressure. Salivation is inhibited with R-(-)-Oxaprotiline, consistent with its anticholinergic properties. R-(-)-Oxaprotiline has similar effects to the established antidepressant compound Levoprotiline and has a shorter onset of action[1].

References

[1] Differences of sympathomimetic and anticholinergic action of OH-maprotiline and its R (-)-enantiomer

Levoprotiline(76496-68-9)Related Product Information

• Levoprtiline
• Maprotiline
• Levoprotiline