2-Deoxy-D-glucose-6-phosphate Chemical Properties

Boiling point:

606.9±65.0 °C(Predicted)

Density 

1.694±0.06 g/cm3(Predicted)

pka

1.84±0.10(Predicted)

2-Deoxy-D-glucose-6-phosphate Usage And Synthesis

Uses

2-Deoxy-D-glucose 6-phosphate is an intermediate of 2-deoxy-D-glucose (2-DG) [1]. 2-Deoxy-D-glucose is incorporated into glycogen[2].

Definition

ChEBI: A deoxyaldohexose phosphate comprising 2-deoxy-D-glucose having the phosphate group at the 6-position.

References

[1] Kuo SC, et al. Inhibition by 2-deoxy-D-glucose of synthesis of glycoprotein enzymes by protoplasts of Saccharomyces: relation to inhibition of sugar uptake and metabolism. J Bacteriol. 1972;111(2):419-429. DOI:10.1128/jb.111.2.419-429.1972
[2] Doenst T, et al. Complexities underlying the quantitative determination of myocardial glucose uptake with 2-deoxyglucose. J Mol Cell Cardiol. 1998;30(8):1595-1604. DOI:10.1006/jmcc.1998.0725
[3] Pajak B, et al. 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents. Int J Mol Sci. 2019;21(1):234. Published 2019 Dec 29. DOI:10.3390/ijms21010234
[4] Paternostro G, et al. Decreased GLUT-4 mRNA content and insulin-sensitive deoxyglucose uptake show insulin resistance in the hypertensive rat heart. Cardiovasc Res. 1995;30(2):205-211. PMID:7585807

2-Deoxy-D-glucose-6-phosphate(3573-50-0)Related Product Information

• D(+)GLUCOSE-1,6-DIPHOSPHATE, TETRACYCLOHEXYLAMMONIUM SALT
• D-GLUCOSAMINE 6-PHOSPHATE
• ROBISON ESTER MONOSODIUM SALT
• N-ACETYL-D-GLUCOSAMINE 6-PHOSPHATE DISODIUM SALT
• D-GLUCOSAMINE 6-PHOSPHATE SODIUM SALT
• <ALPHA>-CYCLODEXTRIN PHOSPHATE SODIUM SA
• D(+)-GLUCOPYRANOSE 6-PHOSPHATE DISODIUM SALT: HYDRATE
• ALPHA-D-GLUCOSE 1,6-DIPHOSPHATE POTASSIUM SALT: HYDRATE
• TREHALOSE 6-PHOSPHATE DIPOTASSIUM SALT
• ALPHA-D-GLUCOSE 1,6-DIPHOSPHATE CYCLOHEXYLAMMONIUM SALT, HYDRATE
• 1,2,3,4-TETRA-O-ACETYL-6-DIPHENYLPHOSPHORYL-BETA-D-MANNOPYRANOSE
• 2-DEOXY-D-GLUCOSE 6-PHOSPHATE SODIUM SALT
• GLUCOSAMINE-6-PHOSPHATE BARIUM SALT
• D-MANNOSE 6-PHOSPHATE BARIUM SALT DIHYDRATE
• D-GLUCOSE-6-PHOSPHATE-UL-14C DISODIUM SALT
• L-ALPHA-PHOSPHATIDYLINOSITOL-3,4,5-TRISPHOSPHATE, DIPALMITOYL-, HEPTAAMMONIUM SALT
• ALPHA-D-GLUCOSE 1,6-DIPHOSPHATE TETRACYCLOHEXYLAMINE SALT
• ALPHA-D-GLUCOSE-6-PHOSPHATE, MONOSODIUM SALT