Isobutyl nitrite Chemical Properties

Boiling point:

66-67 °C(lit.)

Density 

0.87 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.373(lit.)

Flash point:

−6 °F

storage temp. 

0-6°C

form 

clear liquid

color 

Light yellow to Yellow to Orange

Water Solubility 

<0.1 g/100 mL (19 ºC)

Sensitive 

Light Sensitive/Air Sensitive

Merck 

14,5149

BRN 

1699518

Exposure limits

ACGIH: Ceiling 1 ppm

Stability:

Stable. Incompatible with acids, alcohols, strong bases. Decomposes slowly in water. Flammable - incompatible with strong oxidizing agents. Note wide explosion limits. May be light and moisture sensitive. Oxidizer. May explode if heated.

InChIKey

APNSGVMLAYLYCT-UHFFFAOYSA-N

CAS DataBase Reference

542-56-3(CAS DataBase Reference)

IARC

2B (Vol. 122) 2019

NIST Chemistry Reference

(CH3)2CHCH2ONO(542-56-3)

EPA Substance Registry System

Isobutyl nitrite (542-56-3)

Safety Information

Hazard Codes 

F,T,Xi

Risk Statements 

45-11-20/22-68

Safety Statements 

53-45

RIDADR 

UN 2351 3/PG 2

WGK Germany 

3

RTECS 

RA0805000

Hazard Note 

Irritant/Highly Flammable/Keep Cold/Air Sensitive/Light Sensitive

TSCA 

Yes

HazardClass 

3

PackingGroup 

II

HS Code 

29209090

Hazardous Substances Data

542-56-3(Hazardous Substances Data)

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Isobutyl nitrite Usage And Synthesis

Chemical Properties

Isobutyl nitrite is a colourless to pale yellow liquid and has a pleasant and fruity odor.

Uses

Isobutyl nitrite is an alkyl nitrite. It is mainly used in “poppers”, consumed as a recreational drug for their psychoactive effects. Poppers are illegal in many countries, and as a result are commonly sold as air fresheners or deodorizers. Other minor uses of isobutyl nitrite include as an intermediate in the synthesis of aliphatic nitrites, nail polish removers, video head cleaners, fuels, and jet propellants.
Isobutyl nitrite was used to study inhalant-induced immunotoxicity. It is used in the preparation of plasmoquin.

Definition

ChEBI: Isobutyl nitrite is a member of nitrite esters. It derives from an isobutanol.

Preparation

Isobutyl nitrite is synthesized by reacting isobutyl alcohol with sodium nitrite in dilute sulfuric acid (NTP, 1996).

General Description

Isobutyl nitrite is an ester of isobutanol and nitrous acid, which has a various range of household and industrial applications. It is commonly added to a number of household cleaning liquids and air fresheners. As a volatile liquid, it also serves as a "room odorizer" which is widely sold without a prescription.
Besides, Isobutyl nitrite has also been applied in pharmaceuticals, in which it acts as a vasodilator (blood vessel relaxant) and is used medically as part of the emergency antidote for cyanide poisoning.

Air & Water Reactions

Highly flammable. Insoluble in water. Slowly decomposes in water.

Reactivity Profile

An oxidizing agent but can serve as a reducing agent. May begin a vigorous reaction that culminates in a detonation if mixed with reducing agents, including hydrides, sulfides, nitrides, ammonium salts, cyanides, and many fuels.

Fire Hazard

Isobutylnitrite is flammable.

References

https://en.wikipedia.org/wiki/Isobutyl_nitrite
https://www.ncbi.nlm.nih.gov/pubmed/3698454
http://amylnitrite.org/isobutyl

Isobutyl nitrite(542-56-3)Related Product Information

• BUTYL OLEATE
• Isobutyl acrylate
• Methyl acrylate
• Isobutyl acetate
• isobutyl oleate
• 1-Butyl nitrite
• Tris(trimethylsilyl)phosphate
• Triisobutyl phosphate
• Butyl isocyanate
• Isobutyl chloroformate
• Diisobutyl phthalate
• Sodium nitrite
• Pentyl nitrite
• Isoamyl nitrite
• tert-Butyl nitrite
• ISOPROPYL NITRITE
• Nicotinic acid
• Linolenic acid