cinatrin C2
cinatrin C2 Basic information
- Product Name:
- cinatrin C2
- Synonyms:
-
- cinatrin C2
- Pentaric acid, 3-C-carboxy-2-deoxy-2-(1-hydroxydodecyl)-, 1,4-lactone (9CI)
- CAS:
- 136266-36-9
- MF:
- C18H30O8
- MW:
- 374.43
- Mol File:
- 136266-36-9.mol
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cinatrin C2 Chemical Properties
- Boiling point:
- 637.4±55.0 °C(Predicted)
- Density
- 1.272±0.06 g/cm3(Predicted)
- pka
- 2.32±0.60(Predicted)
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cinatrin C2 Usage And Synthesis
Uses
Cinatrin C2 is a phospholipase A2 (PLA2) inhibitor with an IC50 of 800 μM and can be extracted from Circinotrichum falcatisporum RF-641[1][2].
IC 50
PLA2: 800 μM (IC50)
References
[1] Urabe F, et al. Total synthesis of (-)-cinatrin C1 based on an In(OTf)3-catalyzed Conia-Ene reaction. J Org Chem. 2013 Apr 19;78(8):3847-57. DOI:10.1021/jo400263w
[2] Deshmukh, et al. Fungi: A Potential Source of Anti-inflammatory Compounds. In: Satyanarayana, T., Johri, B. (eds) Microorganisms in Sustainable Agriculture and Biotechnology. Springer, Dordrecht.