LENS CULINARIS AGGLUTININ Chemical Properties

Flash point:

40 °C

storage temp. 

2-8°C

form 

buffered aqueous glycerol solution

pka

11.40±0.46(Predicted)

Specific Activity

8,415-11,385nmol/min·mg

Safety Information

Risk Statements 

10

WGK Germany 

1

LENS CULINARIS AGGLUTININ Usage And Synthesis

General Description

Protein tyrosine phosphatase, receptor type, C (PTPRC) or CD45 contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells.

Biochem/physiol Actions

Protein tyrosine phosphatase, receptor type, C (PTPRC) has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.