monensin B
monensin B Basic information
- Product Name:
- monensin B
- Synonyms:
-
- monensin B
- 16-Deethyl-16-methylmonensin
- Monensin, 16-deethyl-16-methyl-
- (2S,3R,4S)-4-((2S,5R,7S,8R,9S)-9-Hydroxy-2-((2S,2'R,3'S,5R,5'R)-5'-((2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl)-2,3'-dimethyloctahydro-[2,2'-bifuran]-5-yl)-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl)-3-methoxy-2-methylpentanoic acid
- (2S,3R,4S)-4-((2S,5R,7S,8R,9S)-9-Hydroxy-2-((2S,2'R,3'S,5R,5'R)-5'-((2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl)-2,3'-dimethyloctahydro-[2,2'-bifuran]-5-yl)-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl)-3-methoxy-2-methylpentanoic acid
- CAS:
- 30485-16-6
- MF:
- C35H60O11
- MW:
- 656.85
- Mol File:
- 30485-16-6.mol
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monensin B Chemical Properties
- Boiling point:
- 758.1±60.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 4.26±0.27(Predicted)
- form
- Solid
- color
- White to off-white
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monensin B Usage And Synthesis
Uses
Monensin B is a polyketide produced by Streptomyces cinnamonensis. Fermentations of Streptomyces cinnamonensis produce a mixture of Monensin A and Monensin B in a ratio dependent upon the relative concentrations of ethylmalonyl-CoA and methylmalonyl-CoA[1].
References
[1] H Liu, et al. Role of crotonyl coenzyme A reductase in determining the ratio of polyketides monensin A and monensin B produced by Streptomyces cinnamonensis. J Bacteriol. 1999 Nov;181(21):6806-13. DOI:10.1128/JB.181.21.6806-6813.1999
monensin BSupplier
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