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POLYBROMINATEDDIPHENYLETHER

Basic information Biological functions Safety Supplier Related

POLYBROMINATEDDIPHENYLETHER Basic information

Product Name:
POLYBROMINATEDDIPHENYLETHER
Synonyms:
  • POLYBROMINATEDDIPHENYLETHER
  • Phenol, 2,3,4,5-tetrabromo-6-(3,5-dibromo-2-hydroxyphenoxy)-
CAS:
80246-27-1
MF:
C12H4Br6O3
MW:
675.58
Mol File:
80246-27-1.mol
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POLYBROMINATEDDIPHENYLETHER Chemical Properties

Boiling point:
454.5±45.0 °C(Predicted)
Density 
2.659±0.06 g/cm3(Predicted)
pka
4.67±0.50(Predicted)
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POLYBROMINATEDDIPHENYLETHER Usage And Synthesis

Biological functions

Reduced serum thyroxine levels and thyroid follicular cell hyperplasia were observed in rats and mice orally exposed to lower brominated PBDE mixtures.PBDE congeners BDE-19 and -10 inhibit AR binding.BDE-99 treatment during pregnancy reduced the estradiol-17β and testosterone levels in male offspring in rats,and affected the progesterone and estrogen receptor (ER)-α and -β levels in the uterus of female offspring.

Description

PBDEs are organobromine compounds used as flame retardants, and they show antiandrogenic and antithyroid activities.

Physical properties

Molecular formula C12H(10- x)BrxO. Soluble in acetone and benzene.

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