AC-ASP-MET-GLN-ASP-PNA
AC-ASP-MET-GLN-ASP-PNA Basic information
- Product Name:
- AC-ASP-MET-GLN-ASP-PNA
- Synonyms:
-
- CASPASE 3 SUBSTRATE 1, CHROMOGENIC
- AC-DMQD-PNA
- AC-ASP-MET-GLN-ASP-PNA
- CAS:
- 907589-02-0
- MF:
- C26H35N7O12S
- MW:
- 669.66
- Product Categories:
-
- peptide
- Mol File:
- Mol File
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AC-ASP-MET-GLN-ASP-PNA Chemical Properties
- Sequence
- Ac-Asp-Met-Gln-Asp-{pNA}
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AC-ASP-MET-GLN-ASP-PNA Usage And Synthesis
Uses
Ac-DMQD-pNA is a peptide substrate. Both of the recombinant CgCaspase-1 (rCgCaspase-1) and the C-terminus of CgCaspase-1 (rCgCaspase-1-C) exhibits similar caspase activity towards proteolytic substrate Ac-DMQD-pNA and Ac-DEVD-pNA (HY-P1006)[1][2].
References
[1] Fang B, et al. Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition. J Mol Biol. 2006 Jul 14;360(3):654-66. DOI:10.1016/j.jmb.2006.05.041
[2] Lu G, et al. The self-activation and LPS binding activity of executioner caspase-1 in oyster Crassostrea gigas. Dev Comp Immunol. 2017 Dec;77:330-339. DOI:10.1016/j.dci.2017.09.002
AC-ASP-MET-GLN-ASP-PNASupplier
GL Biochem (Shanghai) Ltd
- Tel
- 21-61263452 13641803416
- ymbetter@glbiochem.com
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
- Tel
- meitaochem@126.com
- meitaochem@126.com
Hangzhou Beiputai Biopharmaceutical Co., Ltd
- Tel
- 0571-85350119 15888826472
- bptsales@163.com