Basic information Safety Supplier Related

7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL

Basic information Safety Supplier Related

7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL Basic information

Product Name:
7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL
Synonyms:
  • 7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-7-OL
  • 7,8,9,10-tetrahydro-benzo(a)pyren-7-o
  • 7-Hydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene
  • 7,8,9,10-TETRAHYDROBENZO(A)PYREN-7-OL, 9 9%
  • Benzo[a]pyren-7-ol, 7,8,9,10-tetrahydro-
  • 7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol
CAS:
6272-55-5
MF:
C20H16O
MW:
272.34
Product Categories:
  • Alcohols
  • C9 to C30
  • Oxygen Compounds
  • Building Blocks
  • C11 to C30+
  • Chemical Synthesis
  • Organic Building Blocks
  • Oxygen Compounds
Mol File:
6272-55-5.mol
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7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL Chemical Properties

Melting point:
142-144 °C(lit.)
Boiling point:
508.5±19.0 °C(Predicted)
Density 
1.323±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.2 mg/ml
form 
A crystalline solid
pka
14.36±0.20(Predicted)
color 
Light brown to brown
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Safety Information

WGK Germany 
3
RTECS 
DJ8304000

MSDS

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7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL Usage And Synthesis

Description

7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is a benzopyrene derivative that is activated by hepatic cytosol into electrophilic sulfuric acid esters, which are capable of forming covalent DNA adducts and inducing mutations.

Chemical Properties

Yellow Solid

Uses

7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is a benzopyrene derivative that is activated by hepatic cytosol into electrophilic sulfuric acid esters, which are capable of forming covalent DNA adducts and inducing mutations.[Cayman Chemical]

Uses

7,8,9,10-Tetrahydro-benzo[a]pyren-7-ol is a Benzopyrene (B205800) derivative, activated by hepatic cytosol.

General Description

7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol (7-hydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene), a polycyclic aromatic hydrocarbon (PAH), is a substituted benzopyrene. Its bromination reaction with N-bromosaccharin (NBSac) has been investigated. The sulfotransferase-assisted activation of 7-hydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene to form electrophilic, mutagenic, or tumorigenic sulfuric acid ester metabolite, which binds covalently to DNA and leads to mutation, has been reported.

7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OLSupplier

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