1-BOC-1,8-DIAMINOOCTANE Chemical Properties

Boiling point:

356.3±25.0 °C(Predicted)

Density 

0.942±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

Chloroform, Methanol

form 

Solid

pka

12.94±0.46(Predicted)

color 

Off-White

InChI

InChI=1S/C13H28N2O2/c1-13(2,3)17-12(16)15-11-9-7-5-4-6-8-10-14/h4-11,14H2,1-3H3,(H,15,16)

InChIKey

BEHVGNKIRNVBPF-UHFFFAOYSA-N

SMILES

C(OC(C)(C)C)(=O)NCCCCCCCCN

Safety Information

Hazard Codes 

Xi

Hazard Note 

Irritant

HS Code 

2921290090

1-BOC-1,8-DIAMINOOCTANE Usage And Synthesis

Description

tert-butyl (8-aminooctyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs. tert-butyl (8-aminooctyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

tert-Butyl (8-aminooctyl)carbamate (1-Boc-1,8-diaminooctane) can be used as a PROTAC linker in the synthesis of PROTACs. tert-butyl (8-aminooctyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.

1-BOC-1,8-DIAMINOOCTANE(88829-82-7)Related Product Information

• 1-BOC-1,9-DIAMINONONANE
• 1-BOC-1,7-DIAMINOHEPTANE
• 1,8-Diaminooctane
• 1-BOC-1,8-DIAMINOOCTANE
• TERT-BUTYL 1,8-DIAZASPIRO[5.5]UNDECANE-1-CARBOXYLATE
• 2-(3-AMINO-PROPYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• TERT-BUTYL 2-PIPERIDIN-3-YLPYRROLIDINE-1-CARBOXYLATE
• TERT-BUTYL 3-(3-AMINOCYCLOHEXYL)PYRROLIDINE-1-CARBOXYLATE
• TERT-BUTYL 3-(4-AMINOCYCLOHEXYL)PIPERIDINE-1-CARBOXYLATE
• DECAHYDRO-PYRIDO[4,3-B]AZEPINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• TERT-BUTYL 3-(2-AMINOCYCLOHEXYL)PIPERIDINE-1-CARBOXYLATE
• BOC-DIAMINOOCTANE HCL
• TERT-BUTYL 4-(3-AMINOCYCLOHEXYL)PIPERIDINE-1-CARBOXYLATE
• 3-(4-BOC-AMINOBUTYL)PIPERIDINE
• TERT-BUTYL 3-PIPERIDIN-2-YLPYRROLIDINE-1-CARBOXYLATE
• tert-butyl octahydro-1,5-naphthyridine-1(2H)-carboxylate
• TERT-BUTYL 3-(2-AMINOCYCLOHEXYL)PYRROLIDINE-1-CARBOXYLATE
• TERT-BUTYL 9-AMINOBICYCLO[3.3.1]NON-3-YLCARBAMATE