C3A (70-77) Chemical Properties

Density 

1.44±0.1 g/cm3(Predicted)

storage temp. 

−20°C

solubility 

Soluble in DMSO

pka

3.34±0.10(Predicted)

Sequence

Ala-Ser-His-Leu-Gly-Leu-Ala-Arg

Safety Information

WGK Germany 

3

MSDS

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C3A (70-77) Usage And Synthesis

Uses

C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a, exhibits the specificity and 1 to 2% biologic activities of C3a.

Biological Activity

C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a and exhibits C3a specificity and 1 to 2% biological activity.

in vitro

The direct interaction of C3a(70-77) with human mononuclear leukocytes in culture results in a concentration-dependent inhibition of the generation of LIF evoked by mitogens and by the antigen SK-SD.

target

References

[1] Payan DG, et al. Modulation of human lymphocyte function by C3a and C3a(70-77). J Exp Med. 1982 Sep 1;156(3):756-65. DOI:10.1084/jem.156.3.756
[2] Caporale LH, et al. The active site of C3a anaphylatoxin. J Biol Chem. 1980 Nov 25;255(22):10758-63. PMID:6968751

C3A (70-77)(63555-63-5)Related Product Information

• LCAT
• (FMOC-GLU70,ALA71,72,LYS74)-C3A (70-77)
• (BETA-ALA70)-C3A (70-77)
• C3A (70-77)
• Human primary hepatocytes