4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE Chemical Properties

Boiling point:

536.4±50.0 °C(Predicted)

Density 

1.027

storage temp. 

Store at RT

solubility 

Soluble to 100 mM in 1eq. HCl

form 

Powder

pka

7.28±0.10(Predicted)

color 

White to off-white

4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE Usage And Synthesis

Uses

Opioid agonists exert a broad range of effects on the immune system ranging from inflammatory response modulation to opioid and chemokine receptor expression. SNC 162 is a selective δ-opioid receptor agonist.

Definition

ChEBI: 4-[(S)-[(2S,5R)-2,5-dimethyl-4-prop-2-enyl-1-piperazinyl]-phenylmethyl]-N,N-diethylbenzamide is a diarylmethane.

Biological Activity

Potent and selective non-peptide δ -opioid receptor agonist (K i = 0.63 nM). Displays > 8000-fold selectivity over μ -opioid receptors and is centrally active following systemic administration in vivo .

storage

Store at RT

4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE(178803-51-5)Related Product Information

• [(4-METHYLPHENYL)PHENYLMETHYL]PIPERAZINE
• 4-[(AR*)-ALPHA-((2S*,5R*)-4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-HYDROXYBENZYL]-N,N-DIETHYLBENZAMIDE
• N-METHYL-N-[4-[(4-METHYLPIPERAZIN-1-YL)METHYL]BENZYL]AMINE
• (2S,5R)-1-BENZYL-2,5-DIMETHYLPIPERAZINE
• 4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE
• SNC 80