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PACHYCARPINE
PACHYCARPINE Basic information
- Product Name:
- PACHYCARPINE
- Synonyms:
-
- PACHYCARPINE
- d-Sparteine
- Sparteine d-isomer
- (7R,7aR,14R,14aS)-Dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine
- (+)-Sparteine, 98%, from Parochetus communis D. Don
- (1R,2S,9R,10R)-7,15-Diazatetracyclo[7.7.1.02,7.010,15]heptadecane
- (7R)-1,3,4,7,7aβ,8,9,10,11,13,14,14aα-Dodecahydro-7β,14β-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine
- 7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, (7R,7aR,14R,14aS)-
- CAS:
- 492-08-0
- MF:
- C15H26N2
- MW:
- 234.38
- EINECS:
- 805-899-0
- Mol File:
- 492-08-0.mol
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PACHYCARPINE Chemical Properties
- Melting point:
- 201℃
- Boiling point:
- 174°C/8mmHg(lit.)
- Density
- 1.08
- refractive index
- n/D1.527
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform (slightly), Ethanol
- form
- liquid
- pka
- 10.08±0.20(Predicted)
- color
- Colourless to Light Yellow
- λmax
- 202nm(CH3CN)(lit.)
- InChI
- InChI=1S/C15H26N2/c1-3-7-16-11-13-9-12(14(16)5-1)10-17-8-4-2-6-15(13)17/h12-15H,1-11H2/t12-,13-,14-,15+/m1/s1
- InChIKey
- SLRCCWJSBJZJBV-TUVASFSCSA-N
- SMILES
- N12CCCC[C@@]1([H])[C@]1([H])C[C@]([H])(C2)[C@@]2([H])CCCCN2C1
- CAS DataBase Reference
- 492-08-0
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PACHYCARPINE Usage And Synthesis
Uses
(+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.
Safety Profile
Poison by subcutaneous and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.
References
[1] Voitenko S, et al. Effect of (+)-sparteine on nicotinic acetylcholine receptors in the neurons of rat superior cervical ganglion. Mol Pharmacol. 1991 Aug;40(2):180-5. PMID:1715014
PACHYCARPINESupplier
Nanjing Duolong Bio-tech Co.,Ltd. Gold
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Tongchuan Boliante Chemical Co. LTD Gold
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