DIETHYL-12-BROMODODECYLPHOSPHONATE Chemical Properties

Boiling point:

429.5±18.0 °C(Predicted)

Density 

1.124±0.06 g/cm3(Predicted)

DIETHYL-12-BROMODODECYLPHOSPHONATE Usage And Synthesis

Description

diethyl 12-bromodecylphosphonate contains bromine and phosphonate moieties. The bromine is a good leaving group and can undergo nucleophilic substitutions. The phosphonate group acts as chelating agent.

Uses

Diethyl 12-bromododecylphosphonate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

Alkyl-Chain

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DIETHYL-12-BROMODODECYLPHOSPHONATE(264231-28-9)Related Product Information

• DIETHYL 1-DECYLPHOSPHONATE
• DIETHYL 1-OCTYLPHOSPHONATE
• 12-BROMODODECYLPHOSPHONIC ACID
• DIETHYL(1-DODECYL)PHOSPHONATE
• DIETHYL-12-BROMODODECYLPHOSPHONATE