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(R)-3-((1-Methylpyrrolidin-2-yl)Methyl)-1H-indole

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(R)-3-((1-Methylpyrrolidin-2-yl)Methyl)-1H-indole Basic information

Product Name:
(R)-3-((1-Methylpyrrolidin-2-yl)Methyl)-1H-indole
Synonyms:
  • Eletriptan IMP A
  • (R)- 3-[(1-Methyl-2-pyrrolidinyl)Methyl]-1H-Indole
  • (R)-3-((1-Methylpyrrolidin-2-yl)Methyl)-1H-indole
  • Eletriptan Impurity 8 -13
  • Eletriptan Impurity 8
  • Eletriptan Impurity A
  • 1H-Indole, 3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-
CAS:
143322-55-8
MF:
C14H18N2
MW:
214.31
Mol File:
143322-55-8.mol
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(R)-3-((1-Methylpyrrolidin-2-yl)Methyl)-1H-indole Chemical Properties

Melting point:
140-142°C
Boiling point:
365.0±15.0 °C(Predicted)
Density 
1.124±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly) and Methanol (Slightly)
form 
Solid
pka
17.24±0.30(Predicted)
color 
Pale Brown
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(R)-3-((1-Methylpyrrolidin-2-yl)Methyl)-1H-indole Usage And Synthesis

Uses

(R)- 3-[(1-Methyl-2-pyrrolidinyl)methyl]-1H-Indole, is an impurity formed in the preparation of 5-Bromo-3-[(R)-1-methylpyrrolidn-2-ylmethyl]-1H-indole, an intermediate in the synthesis of Eletriptan which is used in the treatment of migraine.

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