1-(2,3-Dihydroxy-4,6-diMethoxyphenyl)-1-propanone Chemical Properties

Melting point:

128°C

Boiling point:

428.7±45.0 °C(Predicted)

Density 

1.240±0.06 g/cm3(Predicted)

solubility 

Dichloromethane, Ethyl Acetate

pka

7.28±0.50(Predicted)

form 

Solid

color 

Yellow

1-(2,3-Dihydroxy-4,6-diMethoxyphenyl)-1-propanone Usage And Synthesis

Chemical Properties

Yellow Solid

Uses

1-(2,3-Dihydroxy-4,6-dimethoxyphenyl)-1-propanone is a reactant used in the preparation of Stigmatellin A (S686780).

Preparation

Preparation by Fries rearrangement of 1,2-dihydroxy-3,5-dimethoxybenzene dipropionate with aluminium chloride in methylene chloride at r.t. for 3 h (94%).