Basic information Safety Supplier Related

4-Hydroxy-TeriflunoMide

Basic information Safety Supplier Related

4-Hydroxy-TeriflunoMide Basic information

Product Name:
4-Hydroxy-TeriflunoMide
Synonyms:
  • 4-Hydroxy-TeriflunoMide
  • (2Z)-2-Cyano-3,4-dihydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide
  • WHYQOFDUXDGMTM-KTKRTIGZSA-N
  • (Z)-2-cyano-3,4-dihydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
  • Teriflunomide 4-Hydroxy
  • 2-Butenamide, 2-cyano-3,4-dihydroxy-N-[4-(trifluoromethyl)phenyl]-, (2Z)-
  • Teriflunomide Impurity 8
CAS:
1058722-45-4
MF:
C12H9F3N2O3
MW:
286.21
Product Categories:
  • Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Inhibitors
Mol File:
1058722-45-4.mol
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4-Hydroxy-TeriflunoMide Usage And Synthesis

Uses

4-Hydroxy-Teriflunomide is a metabolite of Leflunomide (L322750), an immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic (Merck Index).This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.

4-Hydroxy-TeriflunoMideSupplier

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