4-Hydroxy-TeriflunoMide
4-Hydroxy-TeriflunoMide Basic information
- Product Name:
- 4-Hydroxy-TeriflunoMide
- Synonyms:
-
- 4-Hydroxy-TeriflunoMide
- (2Z)-2-Cyano-3,4-dihydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide
- WHYQOFDUXDGMTM-KTKRTIGZSA-N
- (Z)-2-cyano-3,4-dihydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
- Teriflunomide 4-Hydroxy
- 2-Butenamide, 2-cyano-3,4-dihydroxy-N-[4-(trifluoromethyl)phenyl]-, (2Z)-
- Teriflunomide Impurity 8
- CAS:
- 1058722-45-4
- MF:
- C12H9F3N2O3
- MW:
- 286.21
- Product Categories:
-
- Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Inhibitors
- Mol File:
- 1058722-45-4.mol
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4-Hydroxy-TeriflunoMide Usage And Synthesis
Uses
4-Hydroxy-Teriflunomide is a metabolite of Leflunomide (L322750), an immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic (Merck Index).This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.
4-Hydroxy-TeriflunoMideSupplier
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