Basic information Safety Supplier Related

1-Boc-4-amino-4-piperidineacetic acid

Basic information Safety Supplier Related

1-Boc-4-amino-4-piperidineacetic acid Basic information

Product Name:
1-Boc-4-amino-4-piperidineacetic acid
Synonyms:
  • 2-(4-AMINO-1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)ACETIC ACID
  • 1-Boc-4-amino-4-piperidineacetic acid
  • 2-(4-Amino-1-(tert-butoxycarbonyl)
  • 2-[4-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]acetic acid
  • 2-(1-Boc-4-amino-4-piperidyl)acetic Acid
  • 4-Piperidineacetic acid, 4-amino-1-[(1,1-dimethylethoxy)carbonyl]-
  • 2-(4-Amino-1-boc-piperidin-4-yl)acetic Acid
  • 4-Amino-1-[(1,1-dimethylethoxy)carbonyl]-4-piperidineacetic acid
CAS:
1159983-30-8
MF:
C12H22N2O4
MW:
258.31
Product Categories:
  • CHIRAL CHEMICALS
Mol File:
Mol File
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1-Boc-4-amino-4-piperidineacetic acid Chemical Properties

Boiling point:
398.9±27.0 °C(Predicted)
Density 
1.158±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
pka
4.66±0.10(Predicted)
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1-Boc-4-amino-4-piperidineacetic acid Usage And Synthesis

Uses

1-Boc-4-amino-4-piperidineacetic acid can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis


A mixture of 4-oxo-piperidine- 1 -carboxylic acid tert-butyl ester (3.5 g, 17.55 mmol) (Sigma- Aldrich), malonic acid (2.0 g, 19.30 mmol) and ammonium acetate (3.1 g, 40.36 mmol) in n-BuOH was refluxed for 3 h. After cooled, white solid was collected, rinsed with EtOAc and dried in vacuo to provide the title compound 1.61 g (6.2 mmol) in 36% yield.

1-Boc-4-amino-4-piperidineacetic acidSupplier

Tetranov Biopharm
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Nanjing Chemlin Chemical Co., Ltd
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Hangzhou Sage Chemical Co., Ltd.
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Zhengzhou HSH Science & Technology Co., Ltd.
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Tianjin Anhao Biological Technology Co., Ltd.
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