DIBENZYL DIETHYLPHOSPHORAMIDITE Chemical Properties

Boiling point:

131-132 °C(Press: 0.0001 Torr)

Density 

1.06 g/mL at 25 °C(lit.)

vapor pressure 

0.71 psi ( 55 °C)

refractive index 

n20/D 1.545(lit.)

Flash point:

95 °F

storage temp. 

2-8°C

solubility 

Soluble in chloroform.

pka

4.01±0.70(Predicted)

form 

Oil

color 

Clear Colourless to Pale Yellow

Sensitive 

Moisture Sensitive

BRN 

4189915

Stability:

Light Sensitive

CAS DataBase Reference

67746-43-4

Safety Information

Hazard Codes 

Xi

Risk Statements 

10-36/37/38

Safety Statements 

16-26-37/39

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

F 

10-21

HazardClass 

3.2

PackingGroup 

III

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

DIBENZYL DIETHYLPHOSPHORAMIDITE Usage And Synthesis

Chemical Properties

Clear Colourless Liquid

Uses

Dibenzyl N,N-diethylphosphoramidite may be used:

• as phosphitylating reagent in the synthesis of glycosyl phosphites and phosphates
• for phosphorylating the alcohols
• in the preparation of 6-dibenzylphosphate-1,3,5-tri-O-PMB-myo-inositol

Uses

Dibenzyl diethylphosphoramidite is a useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters as well as dibenzyl glycosyl phosphites, which can easily be converted to glycosyl phosphates or used in glycosylation reagents in oligosaccharide synthesis.

General Description

Dibenzyl N,N-diethylphosphoramidite is repoted to be suitable reagent for the efficient 1H-tetrazole-catalyzed ′phosphite-triester′ phosphorylation of the protected serine derivatives.

DIBENZYL DIETHYLPHOSPHORAMIDITE(67746-43-4)Related Product Information

• DIBENZYL N,N-DIMETHYLPHOSPHORAMIDITE
• BIS[1-(2-NITROPHENYL)ETHYL] N,N-DIISOPROPYLPHOSPHORAMIDITE
• Di-p-Chlorobenzyl N,N-Diisopropylphosphoramidite
• DIBENZYL DIISOPROPYLPHOSPHORAMIDITE
• DIBENZYL DIETHYLPHOSPHORAMIDITE