Cetilistat Impurity 1 Chemical Properties

InChI

InChI=1S/C21H31NO3/c1-3-4-5-6-7-8-9-10-11-12-15-24-21-22-19-14-13-17(2)16-18(19)20(23)25-21/h13-14,16H,3-12,15H2,1-2H3

InChIKey

JWCDCQUAOAQERS-UHFFFAOYSA-N

SMILES

N1C2=CC=C(C)C=C2C(=O)OC=1OCCCCCCCCCCCC

Cetilistat Impurity 1 Usage And Synthesis

Description

Cetilistat impurity 1 is also known as Cetilistat Impurity 8 or 2-(dodecyloxy)-6-methyl-4H-benzo[d][1, 3]oxazin-4-one. This compound is an impurity of Cetilistat which is an inhibitor of pancreatic lipase, and acts as an effective anti-obesity agent. Cetilistat inhibits rat and human pancreatic lipase activity with IC50s of 54.8 nM, and 5.95 nM, respectively.