5-Ethyl-4-thiouridine
5-Ethyl-4-thiouridine Basic information
- Product Name:
- 5-Ethyl-4-thiouridine
- Synonyms:
-
- 5-Ethyl-4-thiouridine
- Uridine, 5-ethyl-4-thio- (9CI)
- 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one
- CAS:
- 148744-32-5
- MF:
- C11H16N2O5S
- MW:
- 288.32
- Mol File:
- 148744-32-5.mol
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5-Ethyl-4-thiouridine Usage And Synthesis
Uses
5-Ethyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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