Pyrene -PEG4-acid Chemical Properties

Boiling point:

744.5±60.0 °C(Predicted)

Density 

1.28±0.1 g/cm3(Predicted)

solubility 

Soluble in DMSO, DMF, DCM

pka

4.28±0.10(Predicted)

Pyrene -PEG4-acid Usage And Synthesis

Description

Pyrene-PEG-acid is a pyrene labeled PEG linker for the surface functionalization of carbon nanotube and graphene, graphene oxide, reduced graphene oxide. A strong pi-pi stacking is formed between the pyrene and the aromatic rings on single wall and multi-walled carbon nanotubes.

Uses

Pyrene-amido-PEG4-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Pyrene -PEG4-acid(1817735-34-4)Related Product Information

• Pyrene-PEG4-Propargyl
• Pyrene -PEG5-OH
• Pyrene -PEG5-propargyl
• Pyrene -PEG3-azide
• Pyrene-PEG3-Propargyl
• Pyrene -PEG2-azide
• Pyrene-PEG2-OH
• Pyrene-PEG2-COOH
• Pyrene azide 2
• Pyrene-PEG5-N3
• Pyrene-PEG2-Propargyl
• Pyrene-PEG4-OH
• Pyrene-PEG4-N3
• Pyrene-PEG5-COOH
• Pyrene-PEG3-OH
• Pyrene-PEG2-N3
• Pyrene-PEG3-COOH