ChemicalBook > Product Catalog > Pharmaceutical intermediates > Bulk Drug Intermediates > Benzamide, N,N'-1,3-phenylenebis[4-amino-
Benzamide, N,N'-1,3-phenylenebis[4-amino-
Benzamide, N,N'-1,3-phenylenebis[4-amino- Basic information
- Product Name:
- Benzamide, N,N'-1,3-phenylenebis[4-amino-
- Synonyms:
-
- Benzamide, N,N'-1,3-phenylenebis[4-amino-
- GI-560708
- CAS:
- 2362-25-6
- MF:
- C20H18N4O2
- MW:
- 346.38252
- Mol File:
- 2362-25-6.mol
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Benzamide, N,N'-1,3-phenylenebis[4-amino- Usage And Synthesis
Uses
BCR-ABL-IN-11 (Compound 2) is a BCR-ABL inhibitor. BCR-ABL-IN-11 shows anticancer activity against chronic myelogenous leukemia (CML) (IC50 of 129.61 μM for K562 cells)[1].
References
[1] Peng H, et al. Identification of novel inhibitors of BCR-ABL tyrosine kinase via virtual screening. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3693-9. DOI:10.1016/j.bmcl.2003.08.014
Benzamide, N,N'-1,3-phenylenebis[4-amino-Supplier
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