R(-)-DENOPAMINE
R(-)-DENOPAMINE Basic information
- Product Name:
- R(-)-DENOPAMINE
- Synonyms:
-
- (-)-(r)-1-(p-hydroxyphenyl)-2-((3,4-dimethoxyphenethyl)amino)ethanol
- alpha-(((2-(3,4-dimethoxyphenyl)ethyl)amino)methyl)-4-hydroxy-benzenemethano
- kalgut
- (-)-α-(3,4-dimethoxyphenethylaminomethyl)-4-hydroxy-benzyl-alcohol
- Benzenemethanol, α-[[[2-(3,4-dimethoxyphenyl)ethyl]amino]methyl]-4-hydroxy-, (R)-
- Benzenemethanol, α-[[[2-(3,4-dimethoxyphenyl)ethyl]amino]methyl]-4-hydroxy-, (αR)-
- Carguto
- TA 064
- CAS:
- 71771-90-9
- MF:
- C18H23NO4
- MW:
- 317.38
- Mol File:
- 71771-90-9.mol
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R(-)-DENOPAMINE Chemical Properties
- Melting point:
- 135°C
- Boiling point:
- 456.67°C (rough estimate)
- Density
- 1.1949 (rough estimate)
- refractive index
- 1.5740 (estimate)
- storage temp.
- 2-8°C
- solubility
- DMSO: 26 mg/mL, soluble
- form
- powder
- pka
- 9.97±0.26(Predicted)
- color
- white
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 62-63
- Safety Statements
- 22-36/37/39-45
- WGK Germany
- 3
- RTECS
- DA4795470
MSDS
- Language:English Provider:SigmaAldrich
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R(-)-DENOPAMINE Usage And Synthesis
Description
Denopamine is a potent orally-active cardiotonic with selective effects on the beta, adrenergic receptors. Unlike isoproterenol or dobutamine, denopamine’s positive inotropic activity is not mediated through the release of catecholamines; its lack of effect on heart rate and myocardial oxygen consumption thus offers significant advantages in the management of congestive heart failure.
Originator
Tanabe Seiyaku (Japan)
Uses
R(-)-Denopamine has been used as an β-adrenergic agonist to study its effects on contractility in isolated lymphatic vessels (LVs).
Definition
ChEBI: Denopamine is a dimethoxybenzene.
brand name
Kalgut
Biochem/physiol Actions
Denopamine is a cardiotonic drug.
R(-)-DENOPAMINE Preparation Products And Raw materials
Raw materials
R(-)-DENOPAMINESupplier
J & K SCIENTIFIC LTD.
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LGM Pharma
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Nanjing Sunlida Biological Technology Co., Ltd.
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Sigma-Aldrich
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Raw material medicin reagent co.,Ltd
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