2-LINOLEOYL-RAC-GLYCEROL Chemical Properties

Melting point:

9°C

Boiling point:

485.0±40.0 °C(Predicted)

Density 

0.981±0.06 g/cm3(Predicted)

Flash point:

2℃

storage temp. 

-20°C

solubility 

Chloroform (Slightly), DMF (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)

form 

Oil

pka

13.54±0.10(Predicted)

color 

Colourless to Pale Yellow

BRN 

1715064

Stability:

Temperature Sensitive

CAS DataBase Reference

3443-82-1

Safety Information

Hazard Codes 

F,Xn

Risk Statements 

11-20/21/22-36

Safety Statements 

16-36/37

RIDADR 

UN 1648 3 / PGII

WGK Germany 

3

2-LINOLEOYL-RAC-GLYCEROL Usage And Synthesis

Chemical Properties

Colourless Oil

Uses

2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor. The congener of 2-AG in which a linoleoyl group replaces the arachidonoyl group is 2-linoleoyl glycerol (2-LG), and this compound also appears in vivo in conjunction with 2-AG. Although the intrinsic activity of 2-LG is low, it potentiates the activity of other endocannabinoids, including 2-AG. This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release.

Uses

A fatty acid monoglycerides in vegetable oils with medium unsaturation.

Definition

ChEBI: A 2-monoglyceride where linoleoyl forms the 2-acyl group.

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