(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone
(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone Basic information
- Product Name:
- (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone
- Synonyms:
-
- Benzbromarone Impurity 7 (6-Hydroxy-Benzbromarone)
- (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone
- METHANONE,(3,5-DIBROMO-4-HYDROXYPHENYL)(2-ETHYL-6-HYDROXY-3-BENZOFURANYL)-
- Benzbromarone 6-Hydroxy Impurity
- Benzbromarone Impurity 10 (6-Hydroxy-Benzbromarone）
- Benzbromarone Impurity 10
- BenzbromaroneImpurity7-13C6
- BenzbromaroneImpurity7-13C3-d2
- CAS:
- 152831-00-0
- MF:
- C17H12Br2O4
- MW:
- 440.08
- Mol File:
- 152831-00-0.mol
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(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone Chemical Properties
- Boiling point:
- 444.9±45.0 °C(Predicted)
- Density
- 1.785±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 4.53±0.25(Predicted)
- form
- Solid
- color
- Off-white to light yellow
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(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone Usage And Synthesis
Uses
6-Hydroxybenzbromarone is an angiogenic agent with potent inhibitory effects on cell migration, tubulogenesis and angiogenesis.
Biological Activity
6-Hydroxybenzbromarone is the main metabolite of Benzbromarone, which has a longer half-life and greater pharmacological potency than the parent compound. 6-Hydroxybenzbromarone is an EYA3 inhibitor with IC50 of 21.5 μM.
target
IC50: 21.5 μM (EYA3); metabolite
(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanoneSupplier
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(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone(152831-00-0)Related Product Information
- 2-Ethylbenzofuran
- 3,5-dibromo-4-hydroxyBenzoyl chloride
- (6-BroMo-2-ethyl-3-benzofuranyl)(3,5-dibroMo-4-hydroxyphenyl)Methanone
- Benzobromoma impurity 1
- bromobenzarone
- 3,5-Dibromo-4-hydroxybenzoic acid
- Benzobromoma impurity 4
- Benzbromarone
- Benzobromoma impurity 3
- Benzbromarone Impurity 3
- Benzbromarone D5
- Benzobromoma impurity 2