Basic information Safety Supplier Related

(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone

Basic information Safety Supplier Related

(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone Basic information

Product Name:
(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone
Synonyms:
  • Benzbromarone Impurity 7 (6-Hydroxy-Benzbromarone)
  • (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone
  • METHANONE,(3,5-DIBROMO-4-HYDROXYPHENYL)(2-ETHYL-6-HYDROXY-3-BENZOFURANYL)-
  • Benzbromarone 6-Hydroxy Impurity
  • Benzbromarone Impurity 10 (6-Hydroxy-Benzbromarone)
  • Benzbromarone Impurity 10
  • BenzbromaroneImpurity7-13C6
  • BenzbromaroneImpurity7-13C3-d2
CAS:
152831-00-0
MF:
C17H12Br2O4
MW:
440.08
Mol File:
152831-00-0.mol
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(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone Chemical Properties

Boiling point:
444.9±45.0 °C(Predicted)
Density 
1.785±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
pka
4.53±0.25(Predicted)
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(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone Usage And Synthesis

Uses

6-Hydroxybenzbromarone is an angiogenic agent with potent inhibitory effects on cell migration, tubulogenesis and angiogenesis.

Biological Activity

6-Hydroxybenzbromarone is the main metabolite of Benzbromarone, which has a longer half-life and greater pharmacological potency than the parent compound. 6-Hydroxybenzbromarone is an EYA3 inhibitor with IC50 of 21.5 μM.

target

IC50: 21.5 μM (EYA3); metabolite

(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanoneSupplier

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