m-PEG3-Ms
m-PEG3-Ms Basic information
- Product Name:
- m-PEG3-Ms
- Synonyms:
-
- Methyl-PEG2-MS
- 2-(2-Methoxyethoxy)ethyl methanesulfonate
- m-PEG2-Ms
- Ethanol, 2-(2-methoxyethoxy)-, 1-methanesulfonate
- methanesulfonicacid2-(2-methoxyethoxy)ethylester
- CAS:
- 60696-83-5
- MF:
- C6H14O5S
- MW:
- 198.24
- Mol File:
- 60696-83-5.mol
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m-PEG3-Ms Usage And Synthesis
Description
m-PEG3-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
m-PEG2-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
m-PEG3-MsSupplier
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