4-METHOXYPYRIDAZINE Chemical Properties

Melting point:

43-44℃

Boiling point:

244℃

Density 

1.102

Flash point:

89℃

storage temp. 

Sealed in dry,Room Temperature

pka

4.28±0.10(Predicted)

Safety Information

HS Code 

2933998090

4-METHOXYPYRIDAZINE Usage And Synthesis

Uses

4-methoxypyridazine can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Uses

To a solution of 3 ,6-dichloro-4- methoxypyridazine (30 g, 167.59 mmol, 1.00 equiv) and ammonium formate (3 1 g, 491.63 mmol, 2.93 equiv) in MeOH (500 mL) was added 10% palladium on carbon (3 g) catalyst. The mixture was stirred under 1 atmosphere of at rt overnight. The catalyst was removed by filtration and the filtrate was concentrated under vacuum. The residue was triturated in 500 mL of DCM MeOH ( 10: 1 ) and the solid material was filtered out. The filtrate was concentrated under vacuum and the residue was purified on a silica gel column eluted with ethyl acetate/petroleum ether (2:1 to 1: 1) to give 1 5 g (81%) of 4-methoxypyridazine as a brown oil. TLC: petroleum ether: ethyl acetate=2: 1 , Rf=0.1 .

4-METHOXYPYRIDAZINE(20733-11-3)Related Product Information

• 3-CHLORO-5-METHOXYPYRIDAZINE
• 3,6-DICHLORO-4-METHOXYPYRIDAZINE
• Pyridat
• 6-CHLORO-4-METHOXY-3-PHENYL-PYRIDAZINE
• PYRIDAZINE, 3,6-DICHLORO-4-PHENOXY-
• 6-CHLORO-4-METHOXY-3-METHYLPYRIDAZINE
• 4-METHOXYPYRIDAZINE
• 3-CHLORO-6,7-DIHYDRO[1,4]DIOXINO[2,3-C]PYRIDAZINE
• (6-CHLORO-4-METHOXYPYRIDAZIN-3-YL)METHANOL
• METHYL 6-CHLORO-4-METHOXYPYRIDAZINE-3-CARBOXYLATE
• 6-CHLORO-3,4-DIMETHOXYPYRIDAZINE
• 3-CHLORO-4,5-DIMETHOXYPYRIDAZINE
• 6,7-DIHYDRO[1,4]DIOXINO[2,3-C]PYRIDAZINE-3-CARBONITRILE
• AURORA KA-6125
• 3-CHLORO-5-METHOXY-4-PYRIDAZINECARBONITRILE
• 4-ETHOXY-6-METHANESULFINYL-3-METHYLSULFANYL-PYRIDAZINE
• AURORA KA-5213
• AURORA KA-6123