ChemicalBook > Product Catalog > Organic Chemistry > Heterocyclic Compounds > 5-fluoro-1H-pyrimidine-2,4-dione
5-fluoro-1H-pyrimidine-2,4-dione
5-fluoro-1H-pyrimidine-2,4-dione Basic information
- Product Name:
- 5-fluoro-1H-pyrimidine-2,4-dione
- Synonyms:
-
- [13C,15N2]-5-Fluorouracil
- CAS:
- 1189423-58-2
- MF:
- C4H3FN2O2
- MW:
- 130.0772232
- Mol File:
- 1189423-58-2.mol
More
Less
5-fluoro-1H-pyrimidine-2,4-dione Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMSO: slightly soluble; Methanol: slightly soluble
- form
- A solid
- color
- White to off-white
More
Less
5-fluoro-1H-pyrimidine-2,4-dione Usage And Synthesis
Description
5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis.
Uses
Labelled 5-FU, a potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis.
5-fluoro-1H-pyrimidine-2,4-dioneSupplier
ChemStrong Scientific Co.,Ltd
- Tel
- 0755-0755-66853366 13670046396
- sales@chem-strong.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Shanghai Hongye Biotechnology Co. Ltd
- Tel
- 400-9205774
- sales@glpbio.cn
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
- Tel
- 18818260767
- sales@chemegen.com
Energy Chemical
- Tel
- 021-58432009 400-005-6266
- marketing1@energy-chemical.com