Seco-Duocarmycin SA
Seco-Duocarmycin SA Basic information
- Product Name:
- Seco-Duocarmycin SA
- Synonyms:
-
- Seco-Duocarmycin SA
- (S)-Seco-Duocarmycin SA
- (S)SecoDuocarmycin SA,(S) Seco Duocarmycin SA
- Benzo[1,2-b:4,3-b']dipyrrole-2-carboxylic acid, 8-(chloromethyl)-3,6,7,8-tetrahydro-4-hydroxy-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-, methyl ester, (8S)-
- (S)-Methyl 8-(chloromethyl)-4-hydroxy-6-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-3,6,7,8-tetrahydropyrrolo[3,2-e]indole-2-carboxylate
- CAS:
- 152785-82-5
- MF:
- C25H24ClN3O7
- MW:
- 513.93
- Mol File:
- 152785-82-5.mol
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Seco-Duocarmycin SA Chemical Properties
- Boiling point:
- 773.9±60.0 °C(Predicted)
- Density
- 1.458±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- form
- Solid
- pka
- 9.69±0.40(Predicted)
- color
- Light yellow to yellow
- InChIKey
- SDJNZXKVYYJDDM-GFCCVEGCSA-N
- SMILES
- N1C(C(OC)=O)=CC2=C3[C@H](CCl)CN(C(C4=CC5=C(N4)C(OC)=C(OC)C(OC)=C5)=O)C3=CC(O)=C12
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Seco-Duocarmycin SA Usage And Synthesis
Uses
(S)-Seco-Duocarmycin SA is a DNA alkylator, cytotoxic to cancer cells, and acts as a ADC cytotoxin for antibody-drug conjugates[1].
References
[1] Tichenor MS, et al. Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity. J Am Chem Soc. 2007 Sep 5;129(35):10858-69. DOI:10.1021/ja072777z
Seco-Duocarmycin SASupplier
Levena (Suzhou) Biopharma Co., Ltd. Gold
- Tel
- 0512-81877925 051281877925
- info@levena.cn
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 18892239720
- psaitong@jm-bio.com
Abydos Scientific
- Tel
- 025-84767922 18936879710
- sales@abydoscientific.com
Fan De(Beijing) Biotechnology Co., Ltd.
- Tel
- 15911056312
- liming@bio-fount.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com