N-(4-[[(2-HYDROXYETHYL)AMINO]SULFONYL]PHENYL)ACETAMIDE Chemical Properties

Melting point:

126 °C

Density 

1.380±0.06 g/cm3(Predicted)

pka

10.72±0.50(Predicted)

CAS DataBase Reference

20535-76-6

N-(4-[[(2-HYDROXYETHYL)AMINO]SULFONYL]PHENYL)ACETAMIDE Usage And Synthesis

Uses

p18SMI-21 is a novel INK4C inhibitor that specifically blocks the biological activity of p18 protein. p18SMI-21 exerts its anti-gastric acid effect through direct contact, and the intensity of this effect varies with the dose. p18SMI-21 can significantly reduce the proteolytic activity of pepsin under certain conditions. The inhibitory effect of p18SMI-21 is best achieved in direct contact with the substrate. If it contacts the substrate first, the inhibitory effect will be lost[1].

References

[1] [Biochemical studies on camomile components/III. In vitro studies about the antipeptic activity of (--)-alpha-bisabolol (author's transl)] PMID:21

N-(4-[[(2-HYDROXYETHYL)AMINO]SULFONYL]PHENYL)ACETAMIDE(20535-76-6)Related Product Information

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