4-Bromo-1-chloro-2-nitrobenzene Chemical Properties

Melting point:

0°C

Boiling point:

0°C

Density 

2.035 g/cm3(Temp: 16 °C)

Flash point:

0°C

storage temp. 

Sealed in dry,Room Temperature

solubility 

soluble in Methanol

form 

powder to crystal

color 

White to Light yellow

λmax

313nm(H2O)(lit.)

CAS DataBase Reference

16588-24-2

Safety Information

Hazard Codes 

Xi

HazardClass 

IRRITANT

HS Code 

2904990090

4-Bromo-1-chloro-2-nitrobenzene Usage And Synthesis

Uses

4-Bromo-1-chloro-2-nitrobenzene (5-Bromo-2-chloronitrobenzene) is a pharmaceutical intermediate compound used in the preparation of vismodegib, a molecular inhibitor of the Hedgehog signalling pathway approved for the treatment of metastatic and locally advanced basal cell carcinoma (BCC).

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