4-(4-FLUORO-PHENYL)-3-OXO-BUTYRIC ACID ETHYL ESTER
4-(4-FLUORO-PHENYL)-3-OXO-BUTYRIC ACID ETHYL ESTER Basic information
- Product Name:
- 4-(4-FLUORO-PHENYL)-3-OXO-BUTYRIC ACID ETHYL ESTER
- Synonyms:
-
- 4-(4-FLUORO-PHENYL)-3-OXO-BUTYRIC ACID ETHYL ESTER
- 4-(4-Fluorophenyl)-3-oxobutanoic acid ethyl ester
- Benzenebutanoic acid, 4-fluoro-β-oxo-, ethyl ester
- Ethyl 4-fluorophenylacethylacetate
- Ethyl 4- (4-fluorophenyl) -3-oxobutyrate
- CAS:
- 221121-37-5
- MF:
- C12H13FO3
- MW:
- 224.23
- Mol File:
- 221121-37-5.mol
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4-(4-FLUORO-PHENYL)-3-OXO-BUTYRIC ACID ETHYL ESTER Chemical Properties
- Boiling point:
- 295.5±20.0 °C(Predicted)
- Density
- 1.161±0.06 g/cm3(Predicted)
- pka
- 10.35±0.46(Predicted)
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4-(4-FLUORO-PHENYL)-3-OXO-BUTYRIC ACID ETHYL ESTER Usage And Synthesis
Uses
Ethyl 4-(4-Fluorophenyl)-3-oxobutanoate is used in the synthesis of novel pyridinone derivatives as non-nucleoside reverse transcriptase inhibitors with high potency against NNRTI-resistant HIV-1 strains. Also used in the structural evaluation of 2-substituted 5-hydroxyindole 3-carboxylates as potent inhibitors of human 5-lipoxygenase.
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