Basic information Safety Supplier Related

N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE

Basic information Safety Supplier Related

N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE Basic information

Product Name:
N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE
Synonyms:
  • N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE
  • PHCCC
  • (1aS,7E,7aS)-7,7a-Dihydro-7-(hydroxyimino)-N-phenylbenzo[b]cyclopropa[e]pyran-1a(1H)-carboxamide
  • (1aS,7E,7aS)-7-hydroxyimino-N-phenyl-1,7a-dihydrocyclopropa[b]chromene-1a-carboxamide
  • Benzo[b]cyclopropa[e]pyran-1a(1H)-carboxamide, 7,7a-dihydro-7-(hydroxyimino)-N-phenyl-, (1aS,7E,7aS)-
CAS:
1161205-27-1
MF:
C17H14N2O3
MW:
294.3
Product Categories:
  • Glutamate
Mol File:
Mol File
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N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE Chemical Properties

Boiling point:
579.1±50.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
Store at RT
pka
10.79±0.40(Predicted)
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N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE Usage And Synthesis

Biological Activity

Group I metabotropic glutamate receptor antagonist (IC 50 ~ 3 μ M); 67 times more potent than (S)-4-carboxyphenylglycine ((S)-4-Carboxyphenylglycine). Also a positive allosteric modulator for mGlu 4a ; potentiates L-AP4-mediated inhibition of striatopallidal synaptic transmission in vitro . Displays antiParkinsonian effects in rats in vivo .

N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDESupplier

Shanghai Boyle Chemical Co., Ltd.
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Ascent Scientific
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